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Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case

Hashimoto thyroiditis (HT) is an autoimmune disorder characterized by inadequate thyroid hormone production. A fibrous variant is one of the rarest entities of Hashimoto's thyroiditis disease. A 42 -year-old female patient presented to our service with neck swelling associated with difficulty s...

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Autores principales: Almalali, Maryam Isa Ahmed, Takrouni, Arwa Omar, Alqattan, Abeer Ali, Alsolami, Sana, Salman, Jasim Maki Jasim, Aljehani, Mohammed Maher Mousa, Albaqami, Rakan Mohammad J., Alyahyaei, Abdulrahman Mohammad, Alrasheed, Fathi Aysh Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289414/
https://www.ncbi.nlm.nih.gov/pubmed/35860079
http://dx.doi.org/10.1016/j.amsu.2022.104019
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author Almalali, Maryam Isa Ahmed
Takrouni, Arwa Omar
Alqattan, Abeer Ali
Alsolami, Sana
Salman, Jasim Maki Jasim
Aljehani, Mohammed Maher Mousa
Albaqami, Rakan Mohammad J.
Alyahyaei, Abdulrahman Mohammad
Alrasheed, Fathi Aysh Abdullah
author_facet Almalali, Maryam Isa Ahmed
Takrouni, Arwa Omar
Alqattan, Abeer Ali
Alsolami, Sana
Salman, Jasim Maki Jasim
Aljehani, Mohammed Maher Mousa
Albaqami, Rakan Mohammad J.
Alyahyaei, Abdulrahman Mohammad
Alrasheed, Fathi Aysh Abdullah
author_sort Almalali, Maryam Isa Ahmed
collection PubMed
description Hashimoto thyroiditis (HT) is an autoimmune disorder characterized by inadequate thyroid hormone production. A fibrous variant is one of the rarest entities of Hashimoto's thyroiditis disease. A 42 -year-old female patient presented to our service with neck swelling associated with difficulty swallowing; she was discovered to have an enlarged thyroid gland with mass effect. She underwent an ultrasound and fine-needle aspiration (FNA), which was consistent with Hashimoto's thyroiditis -Bethesda category II-. Due to compressive symptoms, we proceeded to total thyroidectomy. The final histopathology revealed numerous polymorphic lymphoid cells, plasma cells, follicular cells, and scattered Hürthle cells, characteristic of fibrous variants. The surgery was complicated with voice hoarseness and hypocalcemia, which was managed successfully with corticosteroids and calcium supplements. The mainline treatment of HT is medical, but surgical intervention can be considered in some cases. A multidisciplinary approach is needed for successful management. Continuous patient monitoring post-operatively is vital to detect and intervene with early surgical complications.
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spelling pubmed-92894142022-07-19 Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case Almalali, Maryam Isa Ahmed Takrouni, Arwa Omar Alqattan, Abeer Ali Alsolami, Sana Salman, Jasim Maki Jasim Aljehani, Mohammed Maher Mousa Albaqami, Rakan Mohammad J. Alyahyaei, Abdulrahman Mohammad Alrasheed, Fathi Aysh Abdullah Ann Med Surg (Lond) Case Report Hashimoto thyroiditis (HT) is an autoimmune disorder characterized by inadequate thyroid hormone production. A fibrous variant is one of the rarest entities of Hashimoto's thyroiditis disease. A 42 -year-old female patient presented to our service with neck swelling associated with difficulty swallowing; she was discovered to have an enlarged thyroid gland with mass effect. She underwent an ultrasound and fine-needle aspiration (FNA), which was consistent with Hashimoto's thyroiditis -Bethesda category II-. Due to compressive symptoms, we proceeded to total thyroidectomy. The final histopathology revealed numerous polymorphic lymphoid cells, plasma cells, follicular cells, and scattered Hürthle cells, characteristic of fibrous variants. The surgery was complicated with voice hoarseness and hypocalcemia, which was managed successfully with corticosteroids and calcium supplements. The mainline treatment of HT is medical, but surgical intervention can be considered in some cases. A multidisciplinary approach is needed for successful management. Continuous patient monitoring post-operatively is vital to detect and intervene with early surgical complications. Elsevier 2022-06-23 /pmc/articles/PMC9289414/ /pubmed/35860079 http://dx.doi.org/10.1016/j.amsu.2022.104019 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Almalali, Maryam Isa Ahmed
Takrouni, Arwa Omar
Alqattan, Abeer Ali
Alsolami, Sana
Salman, Jasim Maki Jasim
Aljehani, Mohammed Maher Mousa
Albaqami, Rakan Mohammad J.
Alyahyaei, Abdulrahman Mohammad
Alrasheed, Fathi Aysh Abdullah
Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
title Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
title_full Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
title_fullStr Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
title_full_unstemmed Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
title_short Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
title_sort autoimmune thyroiditis a fibrous variant of hashimoto's thyroiditis: a rare case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289414/
https://www.ncbi.nlm.nih.gov/pubmed/35860079
http://dx.doi.org/10.1016/j.amsu.2022.104019
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