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Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case
Hashimoto thyroiditis (HT) is an autoimmune disorder characterized by inadequate thyroid hormone production. A fibrous variant is one of the rarest entities of Hashimoto's thyroiditis disease. A 42 -year-old female patient presented to our service with neck swelling associated with difficulty s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289414/ https://www.ncbi.nlm.nih.gov/pubmed/35860079 http://dx.doi.org/10.1016/j.amsu.2022.104019 |
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author | Almalali, Maryam Isa Ahmed Takrouni, Arwa Omar Alqattan, Abeer Ali Alsolami, Sana Salman, Jasim Maki Jasim Aljehani, Mohammed Maher Mousa Albaqami, Rakan Mohammad J. Alyahyaei, Abdulrahman Mohammad Alrasheed, Fathi Aysh Abdullah |
author_facet | Almalali, Maryam Isa Ahmed Takrouni, Arwa Omar Alqattan, Abeer Ali Alsolami, Sana Salman, Jasim Maki Jasim Aljehani, Mohammed Maher Mousa Albaqami, Rakan Mohammad J. Alyahyaei, Abdulrahman Mohammad Alrasheed, Fathi Aysh Abdullah |
author_sort | Almalali, Maryam Isa Ahmed |
collection | PubMed |
description | Hashimoto thyroiditis (HT) is an autoimmune disorder characterized by inadequate thyroid hormone production. A fibrous variant is one of the rarest entities of Hashimoto's thyroiditis disease. A 42 -year-old female patient presented to our service with neck swelling associated with difficulty swallowing; she was discovered to have an enlarged thyroid gland with mass effect. She underwent an ultrasound and fine-needle aspiration (FNA), which was consistent with Hashimoto's thyroiditis -Bethesda category II-. Due to compressive symptoms, we proceeded to total thyroidectomy. The final histopathology revealed numerous polymorphic lymphoid cells, plasma cells, follicular cells, and scattered Hürthle cells, characteristic of fibrous variants. The surgery was complicated with voice hoarseness and hypocalcemia, which was managed successfully with corticosteroids and calcium supplements. The mainline treatment of HT is medical, but surgical intervention can be considered in some cases. A multidisciplinary approach is needed for successful management. Continuous patient monitoring post-operatively is vital to detect and intervene with early surgical complications. |
format | Online Article Text |
id | pubmed-9289414 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-92894142022-07-19 Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case Almalali, Maryam Isa Ahmed Takrouni, Arwa Omar Alqattan, Abeer Ali Alsolami, Sana Salman, Jasim Maki Jasim Aljehani, Mohammed Maher Mousa Albaqami, Rakan Mohammad J. Alyahyaei, Abdulrahman Mohammad Alrasheed, Fathi Aysh Abdullah Ann Med Surg (Lond) Case Report Hashimoto thyroiditis (HT) is an autoimmune disorder characterized by inadequate thyroid hormone production. A fibrous variant is one of the rarest entities of Hashimoto's thyroiditis disease. A 42 -year-old female patient presented to our service with neck swelling associated with difficulty swallowing; she was discovered to have an enlarged thyroid gland with mass effect. She underwent an ultrasound and fine-needle aspiration (FNA), which was consistent with Hashimoto's thyroiditis -Bethesda category II-. Due to compressive symptoms, we proceeded to total thyroidectomy. The final histopathology revealed numerous polymorphic lymphoid cells, plasma cells, follicular cells, and scattered Hürthle cells, characteristic of fibrous variants. The surgery was complicated with voice hoarseness and hypocalcemia, which was managed successfully with corticosteroids and calcium supplements. The mainline treatment of HT is medical, but surgical intervention can be considered in some cases. A multidisciplinary approach is needed for successful management. Continuous patient monitoring post-operatively is vital to detect and intervene with early surgical complications. Elsevier 2022-06-23 /pmc/articles/PMC9289414/ /pubmed/35860079 http://dx.doi.org/10.1016/j.amsu.2022.104019 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Almalali, Maryam Isa Ahmed Takrouni, Arwa Omar Alqattan, Abeer Ali Alsolami, Sana Salman, Jasim Maki Jasim Aljehani, Mohammed Maher Mousa Albaqami, Rakan Mohammad J. Alyahyaei, Abdulrahman Mohammad Alrasheed, Fathi Aysh Abdullah Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case |
title | Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case |
title_full | Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case |
title_fullStr | Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case |
title_full_unstemmed | Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case |
title_short | Autoimmune thyroiditis a fibrous variant of Hashimoto's thyroiditis: A rare case |
title_sort | autoimmune thyroiditis a fibrous variant of hashimoto's thyroiditis: a rare case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289414/ https://www.ncbi.nlm.nih.gov/pubmed/35860079 http://dx.doi.org/10.1016/j.amsu.2022.104019 |
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