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Growth Differentiation Factor 15 Regulates Oxidative Stress-Dependent Ferroptosis Post Spinal Cord Injury by Stabilizing the p62-Keap1-Nrf2 Signaling Pathway

BACKGROUND: Spinal cord injury (SCI) is a severe traumatic disorder of the central nervous system (CNS) that causes irreversible damage to the nervous tissue. The consequent hemorrhage contributed by trauma induces neuronal ferroptosis post SCI, which is an important death mode to mediate neuronal l...

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Detalles Bibliográficos
Autores principales: Xia, Mingjie, Zhang, Qinyang, Zhang, Yanan, Li, Rulin, Zhao, Tianyu, Chen, Lingxia, Liu, Qiangxian, Zheng, Shengnai, Li, Haijun, Qian, Zhanyang, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289442/
https://www.ncbi.nlm.nih.gov/pubmed/35860670
http://dx.doi.org/10.3389/fnagi.2022.905115

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