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Population Pharmacokinetic Modelling for Nifedipine to Evaluate the Effect of Parathyroid Hormone on CYP3A in Patients with Chronic Kidney Disease

PURPOSE: Parathyroid hormone (PTH) can induce the downregulation of CYP3A in chronic kidney disease (CKD). Nevertheless, the effect of PTH on CYP3A-mediated clearance pathways from a clinical perspective remains unclear. METHODS: This study employed population pharmacokinetic (PopPK) modeling to del...

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Detalles Bibliográficos
Autores principales:	Fu, Chengxiao, Pei, Qi, Liang, Wu, Yang, Bo, Li, Wei, Liu, Jun, Tan, Hongyi, Guo, Chengxian, Zhang, Hao, Yang, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289454/ https://www.ncbi.nlm.nih.gov/pubmed/35860523 http://dx.doi.org/10.2147/DDDT.S362607

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