Cargando…

One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study

INTRODUCTION: Bariatric surgeries have shown efficacy in weight reduction, glycemic control and improvement of type-2 diabetes (T2DM) in patients with obesity. We aimed to assess the efficacy of one anastomosis gastric bypass surgery (OAGB) in T2DM patients with body mass index (BMI) < 35 kg/m(2)...

Descripción completa

Detalles Bibliográficos
Autores principales: Amirbeigi, Alireza, Abbaslou, Fereshteh, Talebpour, Mohammad, Soroush, Ahmadreza, Elyasinia, Fezzeh, Zabihi Mahmoudabadi, Hossein, Najjari, Khosrow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289504/
https://www.ncbi.nlm.nih.gov/pubmed/35860068
http://dx.doi.org/10.1016/j.amsu.2022.104102
_version_ 1784748680019968000
author Amirbeigi, Alireza
Abbaslou, Fereshteh
Talebpour, Mohammad
Soroush, Ahmadreza
Elyasinia, Fezzeh
Zabihi Mahmoudabadi, Hossein
Najjari, Khosrow
author_facet Amirbeigi, Alireza
Abbaslou, Fereshteh
Talebpour, Mohammad
Soroush, Ahmadreza
Elyasinia, Fezzeh
Zabihi Mahmoudabadi, Hossein
Najjari, Khosrow
author_sort Amirbeigi, Alireza
collection PubMed
description INTRODUCTION: Bariatric surgeries have shown efficacy in weight reduction, glycemic control and improvement of type-2 diabetes (T2DM) in patients with obesity. We aimed to assess the efficacy of one anastomosis gastric bypass surgery (OAGB) in T2DM patients with body mass index (BMI) < 35 kg/m(2) within a year after surgery. METHODS: In this multicenter retrospective cohort study, 14 T2DM patients with BMI <35 kg/m(2) (females, %: 71.4% (10 of 14), and age, mean (standard deviation): 51.2 (12.3) years) who had underwent OAGB surgery by the same surgeon, were followed at intervals of one, three, six, and 12 months after surgery. The remission rates of T2DM were calculated and the metabolic indices were compared using paired t-test and Wilcoxon rank test. RESULTS: No adverse outcomes were detected 12 months after surgery. Within six months, seven (50%) patients underwent remission (one (7.1%) within one, three (21.4%) within three, and three (21.4%) within six months). Post-operative weight (p < 0.001) and fasting blood glucose (p < 0.01) in all time periods were significantly lower compared to pre-operative values. Hemoglobin A1C (HbA1C) was significantly lower at three- and six-month intervals (p < 0.05) but not at twelve months (p = 0.2). Thyroid-stimulating hormone and triglyceride levels were lower at six months compared to pre-surgical levels (p < 0.05) but cholesterol levels were not different in any of time points (p > 0.05). CONCLUSION: OAGB surgery is associated with weight reduction, glycemic control and a 50% remission rate within six months in patients with diabetes and BMI <35 kg/m(2).
format Online
Article
Text
id pubmed-9289504
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-92895042022-07-19 One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study Amirbeigi, Alireza Abbaslou, Fereshteh Talebpour, Mohammad Soroush, Ahmadreza Elyasinia, Fezzeh Zabihi Mahmoudabadi, Hossein Najjari, Khosrow Ann Med Surg (Lond) Cohort Study INTRODUCTION: Bariatric surgeries have shown efficacy in weight reduction, glycemic control and improvement of type-2 diabetes (T2DM) in patients with obesity. We aimed to assess the efficacy of one anastomosis gastric bypass surgery (OAGB) in T2DM patients with body mass index (BMI) < 35 kg/m(2) within a year after surgery. METHODS: In this multicenter retrospective cohort study, 14 T2DM patients with BMI <35 kg/m(2) (females, %: 71.4% (10 of 14), and age, mean (standard deviation): 51.2 (12.3) years) who had underwent OAGB surgery by the same surgeon, were followed at intervals of one, three, six, and 12 months after surgery. The remission rates of T2DM were calculated and the metabolic indices were compared using paired t-test and Wilcoxon rank test. RESULTS: No adverse outcomes were detected 12 months after surgery. Within six months, seven (50%) patients underwent remission (one (7.1%) within one, three (21.4%) within three, and three (21.4%) within six months). Post-operative weight (p < 0.001) and fasting blood glucose (p < 0.01) in all time periods were significantly lower compared to pre-operative values. Hemoglobin A1C (HbA1C) was significantly lower at three- and six-month intervals (p < 0.05) but not at twelve months (p = 0.2). Thyroid-stimulating hormone and triglyceride levels were lower at six months compared to pre-surgical levels (p < 0.05) but cholesterol levels were not different in any of time points (p > 0.05). CONCLUSION: OAGB surgery is associated with weight reduction, glycemic control and a 50% remission rate within six months in patients with diabetes and BMI <35 kg/m(2). Elsevier 2022-06-27 /pmc/articles/PMC9289504/ /pubmed/35860068 http://dx.doi.org/10.1016/j.amsu.2022.104102 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Cohort Study
Amirbeigi, Alireza
Abbaslou, Fereshteh
Talebpour, Mohammad
Soroush, Ahmadreza
Elyasinia, Fezzeh
Zabihi Mahmoudabadi, Hossein
Najjari, Khosrow
One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study
title One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study
title_full One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study
title_fullStr One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study
title_full_unstemmed One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study
title_short One anastomosis gastric bypass surgery in Type2 diabetes patients with body mass index < 35 kg/m(2): A multi-center retrospective cohort study
title_sort one anastomosis gastric bypass surgery in type2 diabetes patients with body mass index < 35 kg/m(2): a multi-center retrospective cohort study
topic Cohort Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289504/
https://www.ncbi.nlm.nih.gov/pubmed/35860068
http://dx.doi.org/10.1016/j.amsu.2022.104102
work_keys_str_mv AT amirbeigialireza oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy
AT abbasloufereshteh oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy
AT talebpourmohammad oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy
AT soroushahmadreza oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy
AT elyasiniafezzeh oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy
AT zabihimahmoudabadihossein oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy
AT najjarikhosrow oneanastomosisgastricbypasssurgeryintype2diabetespatientswithbodymassindex35kgm2amulticenterretrospectivecohortstudy