Diagnosis of bone giant cell tumor in elderly patient: A case report of an unusual case

BACKGROUND: Giant cell tumor (GCT) of the bone in elderly patients is a very rare bone tumor. CASE PRESENTATION: Radiography of the left antebrachial revealed a lytic lesion, septated, having a soap bubble appearance in the distal epi-meta-diaphysis of the left radius, narrow transitional zone, type-IB geographic destruction, with cortical thinning, no periosteal reaction, no calcified matrix, with soft tissue involvement. MRI examination of the left antebrachial showed a lesion with partially ill-defined margins, irregular margins, in the left distal epi-meta-diaphysis, accompanied by soft tissue protrusion, which was hypointense on T1WI, iso to hyperintense on T2WI/FAT SAT which partially formed fluids level, the area of diffusion was limited on DWI. After the administration of contrast administration, improvement appeared, the lesion appeared to extend to the articular surface of the left radius bone. Histopathological examination showed the distribution and clusters of mononuclear cells, round oval nuclei, fine chromatin, the distribution of multinucleated giant cells with >10 nuclei similar to mononuclear cell nuclei. These findings were keys as giant bone tumor cells. DISCUSSION: A specific examination of the GTC in the elderly needs to be carried out to minimize misdiagnosis. CONCLUSION: Giant cell tumor is also possible be found in elderly patients. Diagnosis is based on clinical findings, radiological examination, and confirmed by histopathology.