PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis

BACKGROUND: Chronic inflammation contributes to approximately 20% of cancers; the underlying mechanisms are still elusive. Here, using an animal model of colitis to colon-cancerous transformation, we demonstrated that endoplasmic reticulum (ER) stress couples with metabolic reprogramming to promote...

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Detalles Bibliográficos
Autores principales: Tao, Jie, Yin, Lin, Wu, Ao, Zhang, Jiaoli, Zhang, Jingpu, Shi, Huichun, Liu, Siyuan, Niu, Liangfei, Xu, Li, Feng, Yanling, Lian, Shixian, Li, Lei, Zeng, Liyan, Meng, Xianmin, Zhou, Xiaohui, Liu, Tiefu, Zhang, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289542/
https://www.ncbi.nlm.nih.gov/pubmed/35860571
http://dx.doi.org/10.3389/fonc.2022.836087

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