Cargando…

Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk

Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis. This study seeks to describe and compare the sociodemographic, clinical, and functional characteristics of At-Risk Mental State (ARMS) for psy...

Descripción completa

Detalles Bibliográficos
Autores principales: Nieto, Lourdes, Domínguez-Martínez, Tecelli, Rosel-Vales, Mauricio, Saracco-Alvarez, Ricardo, Celada-Borja, Cesar, Rascón-Gasca, María Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289544/
https://www.ncbi.nlm.nih.gov/pubmed/35859823
http://dx.doi.org/10.3389/fpsyg.2022.911030
_version_ 1784748689985634304
author Nieto, Lourdes
Domínguez-Martínez, Tecelli
Rosel-Vales, Mauricio
Saracco-Alvarez, Ricardo
Celada-Borja, Cesar
Rascón-Gasca, María Luisa
author_facet Nieto, Lourdes
Domínguez-Martínez, Tecelli
Rosel-Vales, Mauricio
Saracco-Alvarez, Ricardo
Celada-Borja, Cesar
Rascón-Gasca, María Luisa
author_sort Nieto, Lourdes
collection PubMed
description Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis. This study seeks to describe and compare the sociodemographic, clinical, and functional characteristics of At-Risk Mental State (ARMS) for psychosis youth and those with a first- or second-degree relative with psychosis (Familial High-Risk: FHR) in a Mexican sample. Twenty-one ARMS individuals and 21 with FHR were evaluated for sociodemographic characteristics, psychopathological symptoms, and functional impairment. ARMS individuals were significantly younger, had fewer years of schooling, and were more likely to be male than those in the FHR group. Groups did not differ as regards marital status or occupation. The ARMS group showed greater severity of prodromal symptoms, schizotypal personality traits, and general psychopathology than the FHR group. In addition, they reported more premorbid adjustment deficit from early adolescence than the FHR group. Current overall social and role functioning was significantly lower in the ARMS group. Findings are consistent with ARMS studies from other countries. First- or second-degree relatives of patients with psychosis should be considered a vulnerable group as they display several symptoms of general psychopathology and may experience social adjustment problems in their adult lives. The lack of early detection and intervention psychosis programs in Mexico underlines the need to prioritize the development of preventive strategies to help close the care gap.
format Online
Article
Text
id pubmed-9289544
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-92895442022-07-19 Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk Nieto, Lourdes Domínguez-Martínez, Tecelli Rosel-Vales, Mauricio Saracco-Alvarez, Ricardo Celada-Borja, Cesar Rascón-Gasca, María Luisa Front Psychol Psychology Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis. This study seeks to describe and compare the sociodemographic, clinical, and functional characteristics of At-Risk Mental State (ARMS) for psychosis youth and those with a first- or second-degree relative with psychosis (Familial High-Risk: FHR) in a Mexican sample. Twenty-one ARMS individuals and 21 with FHR were evaluated for sociodemographic characteristics, psychopathological symptoms, and functional impairment. ARMS individuals were significantly younger, had fewer years of schooling, and were more likely to be male than those in the FHR group. Groups did not differ as regards marital status or occupation. The ARMS group showed greater severity of prodromal symptoms, schizotypal personality traits, and general psychopathology than the FHR group. In addition, they reported more premorbid adjustment deficit from early adolescence than the FHR group. Current overall social and role functioning was significantly lower in the ARMS group. Findings are consistent with ARMS studies from other countries. First- or second-degree relatives of patients with psychosis should be considered a vulnerable group as they display several symptoms of general psychopathology and may experience social adjustment problems in their adult lives. The lack of early detection and intervention psychosis programs in Mexico underlines the need to prioritize the development of preventive strategies to help close the care gap. Frontiers Media S.A. 2022-07-04 /pmc/articles/PMC9289544/ /pubmed/35859823 http://dx.doi.org/10.3389/fpsyg.2022.911030 Text en Copyright © 2022 Nieto, Domínguez-Martínez, Rosel-Vales, Saracco-Alvarez, Celada-Borja and Rascón-Gasca. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychology
Nieto, Lourdes
Domínguez-Martínez, Tecelli
Rosel-Vales, Mauricio
Saracco-Alvarez, Ricardo
Celada-Borja, Cesar
Rascón-Gasca, María Luisa
Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
title Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
title_full Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
title_fullStr Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
title_full_unstemmed Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
title_short Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
title_sort clinical and functional differences between mexican youth at clinical high risk for psychosis and with familial high risk
topic Psychology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289544/
https://www.ncbi.nlm.nih.gov/pubmed/35859823
http://dx.doi.org/10.3389/fpsyg.2022.911030
work_keys_str_mv AT nietolourdes clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk
AT dominguezmartineztecelli clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk
AT roselvalesmauricio clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk
AT saraccoalvarezricardo clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk
AT celadaborjacesar clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk
AT rascongascamarialuisa clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk