Raloxifene induced keratopathy: A case report

PURPOSE: We report a case of corneal verticillata in a patient who had been taking raloxifene for a prolonged period. To our knowledge, this is the first case report of an ocular side effect of raloxifene. OBSERVATIONS: A 69-year-old female patient presented to our clinic for her routine eye check-u...

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Detalles Bibliográficos
Autores principales: Park, Ji Min, Jeong, Kyeong Do, Kang, Min-Ji, Lee, Jee Hye, Kim, Jae Suk, Hwang, Je Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289629/
https://www.ncbi.nlm.nih.gov/pubmed/35859701
http://dx.doi.org/10.1016/j.ajoc.2022.101661
Descripción
Sumario:PURPOSE: We report a case of corneal verticillata in a patient who had been taking raloxifene for a prolonged period. To our knowledge, this is the first case report of an ocular side effect of raloxifene. OBSERVATIONS: A 69-year-old female patient presented to our clinic for her routine eye check-up. On slit-lamp examination, whorl-like subepithelial deposits were observed in the bilateral corneas. She was diagnosed with corneal verticillata (vortex keratopathy) caused by raloxifene. A follow-up evaluation was conducted after discontinuation of the drug; however, the corneal opacity did not improve. CONCLUSIONS AND IMPORTANCE: Patients with corneal verticillata should be asked regarding any intake of raloxifene for osteoporosis, as it may cause corneal verticillata.

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