Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain

Over a time period of 18 months an Enterobacter hormaechei sequence type (ST) 90, harboring a bla(OXA-436) carbapenemase gene, was isolated from seven patients at Odense University Hospital, Denmark. The patients were all from the same department, but there was no apparent direct epidemiological lin...

Descripción completa

Detalles Bibliográficos
Autores principales: Raun-Petersen, Christina, Toft, Annette, Nordestgaard, Mette Marie, Holm, Anette, Overballe-Petersen, Søren, Hammerum, Anette M., Hasman, Henrik, Justesen, Ulrik Stenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Outbreak Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289634/
https://www.ncbi.nlm.nih.gov/pubmed/35860606
http://dx.doi.org/10.1016/j.infpip.2022.100228
_version_ 1784748711714226176
author Raun-Petersen, Christina
Toft, Annette
Nordestgaard, Mette Marie
Holm, Anette
Overballe-Petersen, Søren
Hammerum, Anette M.
Hasman, Henrik
Justesen, Ulrik Stenz
author_facet Raun-Petersen, Christina
Toft, Annette
Nordestgaard, Mette Marie
Holm, Anette
Overballe-Petersen, Søren
Hammerum, Anette M.
Hasman, Henrik
Justesen, Ulrik Stenz
author_sort Raun-Petersen, Christina
collection PubMed
description Over a time period of 18 months an Enterobacter hormaechei sequence type (ST) 90, harboring a bla(OXA-436) carbapenemase gene, was isolated from seven patients at Odense University Hospital, Denmark. The patients were all from the same department, but there was no apparent direct epidemiological link. Whole genome sequencing (WGS) was performed on all clinical isolates as well as on a number of environmental samples including two E. hormaechei ST90 isolates carrying the bla(OXA-436) gene, which were isolated in samples from two shower drains at the department. These drains were suspected to be the source of the outbreak.
format Online
Article
Text
id pubmed-9289634
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-92896342022-07-19 Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain Raun-Petersen, Christina Toft, Annette Nordestgaard, Mette Marie Holm, Anette Overballe-Petersen, Søren Hammerum, Anette M. Hasman, Henrik Justesen, Ulrik Stenz Infect Prev Pract Outbreak Report Over a time period of 18 months an Enterobacter hormaechei sequence type (ST) 90, harboring a bla(OXA-436) carbapenemase gene, was isolated from seven patients at Odense University Hospital, Denmark. The patients were all from the same department, but there was no apparent direct epidemiological link. Whole genome sequencing (WGS) was performed on all clinical isolates as well as on a number of environmental samples including two E. hormaechei ST90 isolates carrying the bla(OXA-436) gene, which were isolated in samples from two shower drains at the department. These drains were suspected to be the source of the outbreak. Elsevier 2022-06-30 /pmc/articles/PMC9289634/ /pubmed/35860606 http://dx.doi.org/10.1016/j.infpip.2022.100228 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Outbreak Report
Raun-Petersen, Christina
Toft, Annette
Nordestgaard, Mette Marie
Holm, Anette
Overballe-Petersen, Søren
Hammerum, Anette M.
Hasman, Henrik
Justesen, Ulrik Stenz
Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain
title Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain
title_full Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain
title_fullStr Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain
title_full_unstemmed Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain
title_short Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak: when everything goes down the drain
title_sort investigation of an enterobacter hormaechei oxa-436 carbapenemase outbreak: when everything goes down the drain
topic Outbreak Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289634/
https://www.ncbi.nlm.nih.gov/pubmed/35860606
http://dx.doi.org/10.1016/j.infpip.2022.100228
work_keys_str_mv AT raunpetersenchristina investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT toftannette investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT nordestgaardmettemarie investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT holmanette investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT overballepetersensøren investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT hammerumanettem investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT hasmanhenrik investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain
AT justesenulrikstenz investigationofanenterobacterhormaecheioxa436carbapenemaseoutbreakwheneverythinggoesdownthedrain

Ejemplares similares