Highly Parallelized, Multicolor Optogenetic Recordings of Cellular Activity for Therapeutic Discovery Applications in Ion Channels and Disease-Associated Excitable Cells

Optogenetic assays provide a flexible, scalable, and information rich approach to probe compound effects for ion channel drug targets in both heterologous expression systems and associated disease relevant cell types. Despite the potential utility and growing adoption of optogenetics, there remains...

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Detalles Bibliográficos
Autores principales: Borja, Gabriel B., Zhang, Hongkang, Harwood, Benjamin N., Jacques, Jane, Grooms, Jennifer, Chantre, Romina O., Zhang, Dawei, Barnett, Adam, Werley, Christopher A., Lu, Yang, Nagle, Steven F., McManus, Owen B., Dempsey, Graham T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289666/
https://www.ncbi.nlm.nih.gov/pubmed/35860501
http://dx.doi.org/10.3389/fnmol.2022.896320

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