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MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents

MicroRNAs (miRNA, miR-) play important roles in disease development. In this study, we identified an anti-proliferative miRNA, miR-212-5p, that is induced in pulmonary artery smooth muscle cells (PASMCs) and lungs of pulmonary hypertension (PH) patients and rodents with experimental PH. We found tha...

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Detalles Bibliográficos
Autores principales: Chen, Tianji, Sun, Miranda R., Zhou, Qiyuan, Guzman, Alyssa M., Ramchandran, Ramaswamy, Chen, Jiwang, Fraidenburg, Dustin R., Ganesh, Balaji, Maienschein-Cline, Mark, Obrietan, Karl, Raj, J. Usha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289783/
https://www.ncbi.nlm.nih.gov/pubmed/35892089
http://dx.doi.org/10.1016/j.omtn.2022.06.008