Cargando…
Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance
[Image: see text] Prion diseases are a group of neurodegenerative disorders characterized by the accumulation of misfolded prion protein (called PrP(Sc)). Although conversion of the cellular prion protein (PrP(C)) to PrP(Sc) is still not completely understood, most of the therapies developed until n...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289883/ https://www.ncbi.nlm.nih.gov/pubmed/35771181 http://dx.doi.org/10.1021/acs.jmedchem.2c00205 |