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Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance

[Image: see text] Prion diseases are a group of neurodegenerative disorders characterized by the accumulation of misfolded prion protein (called PrP(Sc)). Although conversion of the cellular prion protein (PrP(C)) to PrP(Sc) is still not completely understood, most of the therapies developed until n...

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Detalles Bibliográficos
Autores principales:	Colini Baldeschi, Arianna, Zattoni, Marco, Vanni, Silvia, Nikolic, Lea, Ferracin, Chiara, La Sala, Giuseppina, Summa, Maria, Bertorelli, Rosalia, Bertozzi, Sine Mandrup, Giachin, Gabriele, Carloni, Paolo, Bolognesi, Maria Laura, De Vivo, Marco, Legname, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289883/ https://www.ncbi.nlm.nih.gov/pubmed/35771181 http://dx.doi.org/10.1021/acs.jmedchem.2c00205

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