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Counting Degrons: Lessons From Multivalent Substrates for Targeted Protein Degradation
E3s comprise a structurally diverse group of at least 800 members, most of which target multiple substrates through specific and regulated protein-protein interactions. These interactions typically rely on short linear motifs (SLiMs), called “degrons”, in an intrinsically disordered region (IDR) of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289945/ https://www.ncbi.nlm.nih.gov/pubmed/35860655 http://dx.doi.org/10.3389/fphys.2022.913063 |