An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report

Deficiency of vitamin B12 usually presents with symptoms of anaemia or neurological dysfunction. We report a case of a young lady who was found to be vitamin B12 deficient with massive splenomegaly, haemolytic anaemia, and pancytopenia. She was thoroughly investigated for other causes of similar pre...

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Autores principales: Elhiday, Hisham, Musa, Muzamil, Hussaini, Syed Ahmed, Al-Warqi, Akram, Alfitori, Gamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289965/
https://www.ncbi.nlm.nih.gov/pubmed/35865441
http://dx.doi.org/10.7759/cureus.26058
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author Elhiday, Hisham
Musa, Muzamil
Hussaini, Syed Ahmed
Al-Warqi, Akram
Alfitori, Gamal
author_facet Elhiday, Hisham
Musa, Muzamil
Hussaini, Syed Ahmed
Al-Warqi, Akram
Alfitori, Gamal
author_sort Elhiday, Hisham
collection PubMed
description Deficiency of vitamin B12 usually presents with symptoms of anaemia or neurological dysfunction. We report a case of a young lady who was found to be vitamin B12 deficient with massive splenomegaly, haemolytic anaemia, and pancytopenia. She was thoroughly investigated for other causes of similar presentation. Her symptoms and blood count drastically improved after two weeks of therapy with vitamin B12 supplementation. After reviewing the literature on unusual cases of vitamin B12 deficiency, our case is a very interesting read as it serves as a reminder for health care providers to be alert for these manifestations, which can be treated by simply replacing vitamin B12.
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spelling pubmed-92899652022-07-20 An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report Elhiday, Hisham Musa, Muzamil Hussaini, Syed Ahmed Al-Warqi, Akram Alfitori, Gamal Cureus Internal Medicine Deficiency of vitamin B12 usually presents with symptoms of anaemia or neurological dysfunction. We report a case of a young lady who was found to be vitamin B12 deficient with massive splenomegaly, haemolytic anaemia, and pancytopenia. She was thoroughly investigated for other causes of similar presentation. Her symptoms and blood count drastically improved after two weeks of therapy with vitamin B12 supplementation. After reviewing the literature on unusual cases of vitamin B12 deficiency, our case is a very interesting read as it serves as a reminder for health care providers to be alert for these manifestations, which can be treated by simply replacing vitamin B12. Cureus 2022-06-18 /pmc/articles/PMC9289965/ /pubmed/35865441 http://dx.doi.org/10.7759/cureus.26058 Text en Copyright © 2022, Elhiday et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Elhiday, Hisham
Musa, Muzamil
Hussaini, Syed Ahmed
Al-Warqi, Akram
Alfitori, Gamal
An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report
title An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report
title_full An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report
title_fullStr An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report
title_full_unstemmed An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report
title_short An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report
title_sort unusual presentation of vitamin b12 deficiency associated with massive splenomegaly, hemolytic anemia, and pancytopenia: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289965/
https://www.ncbi.nlm.nih.gov/pubmed/35865441
http://dx.doi.org/10.7759/cureus.26058
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