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Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature

Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical ma...

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Detalles Bibliográficos
Autores principales: Trad, George, Sheikhan, Nazanin, Nguyen, Andrew, Hader, Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290102/
https://www.ncbi.nlm.nih.gov/pubmed/35848077
http://dx.doi.org/10.1177/23247096221111763
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author Trad, George
Sheikhan, Nazanin
Nguyen, Andrew
Hader, Ismail
author_facet Trad, George
Sheikhan, Nazanin
Nguyen, Andrew
Hader, Ismail
author_sort Trad, George
collection PubMed
description Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical management, highest length of survival was reported to be 10 months. We report a case of malignant melanoma with isolated pancreatic metastasis treated with interferon therapy and immunotherapy, with evidence of progressive tumor shrinkage and survival at 38 months.
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spelling pubmed-92901022022-07-19 Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature Trad, George Sheikhan, Nazanin Nguyen, Andrew Hader, Ismail J Investig Med High Impact Case Rep Case Report Isolated pancreatic metastases from melanoma are rare with high mortality rate and account for less than 1% of metastatic melanomas. Treatment options are limited with highest overall survival reported in those with complete surgical resection. Of cases reported in the literature with nonsurgical management, highest length of survival was reported to be 10 months. We report a case of malignant melanoma with isolated pancreatic metastasis treated with interferon therapy and immunotherapy, with evidence of progressive tumor shrinkage and survival at 38 months. SAGE Publications 2022-07-16 /pmc/articles/PMC9290102/ /pubmed/35848077 http://dx.doi.org/10.1177/23247096221111763 Text en © 2022 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Trad, George
Sheikhan, Nazanin
Nguyen, Andrew
Hader, Ismail
Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature
title Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature
title_full Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature
title_fullStr Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature
title_full_unstemmed Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature
title_short Nonsurgical Approach to Isolated Pancreatic Metastatic Malignant Melanoma: A Case Report and Review of the Literature
title_sort nonsurgical approach to isolated pancreatic metastatic malignant melanoma: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290102/
https://www.ncbi.nlm.nih.gov/pubmed/35848077
http://dx.doi.org/10.1177/23247096221111763
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