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Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana

BACKGROUND: Postpartum preeclampsia has been implicated in increasing hospital re-admissions, maternal morbidity, and mortality worldwide. The knowledge of the risk factors of postpartum preeclampsia would be helpful in formulating strategies to aid in the prevention, early diagnosis, and timely tre...

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Autores principales: Fondjo, Linda Ahenkorah, Amoah, Beatrice, Tashie, Worlanyo, Annan, John Jude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290105/
https://www.ncbi.nlm.nih.gov/pubmed/35848351
http://dx.doi.org/10.1177/17455057221109362
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author Fondjo, Linda Ahenkorah
Amoah, Beatrice
Tashie, Worlanyo
Annan, John Jude
author_facet Fondjo, Linda Ahenkorah
Amoah, Beatrice
Tashie, Worlanyo
Annan, John Jude
author_sort Fondjo, Linda Ahenkorah
collection PubMed
description BACKGROUND: Postpartum preeclampsia has been implicated in increasing hospital re-admissions, maternal morbidity, and mortality worldwide. The knowledge of the risk factors of postpartum preeclampsia would be helpful in formulating strategies to aid in the prevention, early diagnosis, and timely treatment of this disorder. Thus, this study aimed to identify the risk factors associated with the development of new-onset postpartum preeclampsia and persistent postpartum preeclampsia in the Ghanaian setting. METHODS: This case–control study was conducted at the Obstetrics and Gynecology units of Komfo Anokye Teaching Hospital and the Kumasi Regional Hospital, both located in the Ashanti Region of Ghana. A total of 65 postpartum preeclamptic women (33 new-onset postpartum preeclampsia and 32 persistent postpartum preeclampsia) and 65 normotensive postpartum mothers were recruited from 48 h to 6 weeks post-delivery. Questionnaires were administered to assess the socio-demographic, lifestyle, obstetric characteristics, and past medical history of the study participants. RESULTS: Physical inactivity (p < 0.0001), infrequent antenatal visits (p < 0.0001), analgesic use (p < 0.0001), and cesarean delivery (p = 0.021) were significantly associated with both the new-onset postpartum preeclampsia and persistent postpartum preeclampsia. Contraceptive use was significantly associated with the development of new-onset postpartum preeclampsia (p < 0.0001) while women with low-birthweight babies are also at high risk of developing persistent postpartum preeclampsia (p < 0.0001). CONCLUSION: Physical inactivity, infrequent antenatal visits, analgesic use, contraceptive use, and cesarean delivery are major predisposing risk factors for the development of postpartum preeclampsia. Screening using these risk factors, close monitoring and follow-up observation of women after delivery would be beneficial in identifying and managing postpartum preeclampsia.
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spelling pubmed-92901052022-07-19 Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana Fondjo, Linda Ahenkorah Amoah, Beatrice Tashie, Worlanyo Annan, John Jude Womens Health (Lond) Maternal Health Considerations: Psychological Physiological Wellbeing BACKGROUND: Postpartum preeclampsia has been implicated in increasing hospital re-admissions, maternal morbidity, and mortality worldwide. The knowledge of the risk factors of postpartum preeclampsia would be helpful in formulating strategies to aid in the prevention, early diagnosis, and timely treatment of this disorder. Thus, this study aimed to identify the risk factors associated with the development of new-onset postpartum preeclampsia and persistent postpartum preeclampsia in the Ghanaian setting. METHODS: This case–control study was conducted at the Obstetrics and Gynecology units of Komfo Anokye Teaching Hospital and the Kumasi Regional Hospital, both located in the Ashanti Region of Ghana. A total of 65 postpartum preeclamptic women (33 new-onset postpartum preeclampsia and 32 persistent postpartum preeclampsia) and 65 normotensive postpartum mothers were recruited from 48 h to 6 weeks post-delivery. Questionnaires were administered to assess the socio-demographic, lifestyle, obstetric characteristics, and past medical history of the study participants. RESULTS: Physical inactivity (p < 0.0001), infrequent antenatal visits (p < 0.0001), analgesic use (p < 0.0001), and cesarean delivery (p = 0.021) were significantly associated with both the new-onset postpartum preeclampsia and persistent postpartum preeclampsia. Contraceptive use was significantly associated with the development of new-onset postpartum preeclampsia (p < 0.0001) while women with low-birthweight babies are also at high risk of developing persistent postpartum preeclampsia (p < 0.0001). CONCLUSION: Physical inactivity, infrequent antenatal visits, analgesic use, contraceptive use, and cesarean delivery are major predisposing risk factors for the development of postpartum preeclampsia. Screening using these risk factors, close monitoring and follow-up observation of women after delivery would be beneficial in identifying and managing postpartum preeclampsia. SAGE Publications 2022-07-16 /pmc/articles/PMC9290105/ /pubmed/35848351 http://dx.doi.org/10.1177/17455057221109362 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Maternal Health Considerations: Psychological Physiological Wellbeing
Fondjo, Linda Ahenkorah
Amoah, Beatrice
Tashie, Worlanyo
Annan, John Jude
Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana
title Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana
title_full Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana
title_fullStr Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana
title_full_unstemmed Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana
title_short Risk factors for the development of new-onset and persistent postpartum preeclampsia: A case–control study in Ghana
title_sort risk factors for the development of new-onset and persistent postpartum preeclampsia: a case–control study in ghana
topic Maternal Health Considerations: Psychological Physiological Wellbeing
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290105/
https://www.ncbi.nlm.nih.gov/pubmed/35848351
http://dx.doi.org/10.1177/17455057221109362
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