Efficient production of a cyclic dipeptide (cyclo-TA) using heterologous expression system of filamentous fungus Aspergillus oryzae

BACKGROUND: Cyclic dipeptides are an important class of natural products owing to their structural diversity and biological activities. In fungi, the cyclo-ring system is formed through the condensation of two α-amino acids via non-ribosomal peptide synthetase (NRPS). However, there are few investig...

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Detalles Bibliográficos
Autores principales: Qi, Jianzhao, Han, Haiyan, Sui, Dan, Tan, Shengnan, Liu, Changli, Wang, Pengchao, Xie, Chunliang, Xia, Xuekui, Gao, Jin-ming, Liu, Chengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290255/
https://www.ncbi.nlm.nih.gov/pubmed/35843946
http://dx.doi.org/10.1186/s12934-022-01872-8

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