Cargando…
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
BACKGROUND: There is considerable evidence for the importance of the DNA methylome in metabolic health, for example, a robust methylation signature has been associated with body mass index (BMI). However, visceral fat (VF) mass accumulation is a greater risk factor for metabolic disease than BMI alo...
Autores principales: | Christiansen, Colette, Tomlinson, Max, Eliot, Melissa, Nilsson, Emma, Costeira, Ricardo, Xia, Yujing, Villicaña, Sergio, Mompeo, Olatz, Wells, Philippa, Castillo-Fernandez, Juan, Potier, Louis, Vohl, Marie-Claude, Tchernof, Andre, Moustafa, Julia El-Sayed, Menni, Cristina, Steves, Claire J., Kelsey, Karl, Ling, Charlotte, Grundberg, Elin, Small, Kerrin S., Bell, Jordana T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290282/ https://www.ncbi.nlm.nih.gov/pubmed/35843982 http://dx.doi.org/10.1186/s13073-022-01077-z |
Ejemplares similares
-
Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans
por: Roberts, Amy L, et al.
Publicado: (2022) -
AKR1C2 and AKR1C3 expression in adipose tissue: Association with body fat distribution and regulatory variants
por: Ostinelli, Giada, et al.
Publicado: (2021) -
Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome
por: Costeira, Ricardo, et al.
Publicado: (2023) -
Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
por: Allum, Fiona, et al.
Publicado: (2015) -
The fecal metabolome as a functional readout of the gut microbiome
por: Zierer, Jonas, et al.
Publicado: (2018)