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Asymmetric Cation‐Olefin Monocyclization by Engineered Squalene–Hopene Cyclases

Squalene–hopene cyclases (SHCs) have great potential for the industrial synthesis of enantiopure cyclic terpenoids. A limitation of SHC catalysis has been the enzymes’ strict (S)‐enantioselectivity at the stereocenter formed after the first cyclization step. To gain enantio‐complementary access to v...

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Detalles Bibliográficos
Autores principales:	Eichenberger, Michael, Hüppi, Sean, Patsch, David, Aeberli, Natalie, Berweger, Raphael, Dossenbach, Sandro, Eichhorn, Eric, Flachsmann, Felix, Hortencio, Lucas, Voirol, Francis, Vollenweider, Sabine, Bornscheuer, Uwe T., Buller, Rebecca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290348/ https://www.ncbi.nlm.nih.gov/pubmed/34346556 http://dx.doi.org/10.1002/anie.202108037

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