Cargando…

Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project

INTRODUCTION: The Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project was conceived to explore innovative complementary strategies to uncover hidden prodromal and mild Alzheimer's disease (AD) dementia cases and to raise awareness both in the general public and among heal...

Descripción completa

Detalles Bibliográficos
Autores principales: Boada, Mercè, Rodrigo, Adrián, Jessen, Frank, Wimblad, Bengt, Kramberger, Milica G., Visser, Pieter Jelle, Simó, Rafael, Rodríguez‐Gomez, Octavio, Ciudin, Andreea, Georges, Jean, Dumas, Annete, Maguire, Peggy, Krivec, David, Wimo, Anders, Valero, Sergi, Alegret, Montserrat, Jamilis, Laura, Zwan, Marissa, Sannemann, Lena, Arrufat, Jordi, Stomrud, Erik, Johansson, Gunilla, Shering, Craig, Glaysher, Bridget, Stewart, Neil, Belger, Mark, Iradier, Fatima, Campo, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290633/
https://www.ncbi.nlm.nih.gov/pubmed/34310061
http://dx.doi.org/10.1002/alz.12441
_version_ 1784748947479199744
author Boada, Mercè
Rodrigo, Adrián
Jessen, Frank
Wimblad, Bengt
Kramberger, Milica G.
Visser, Pieter Jelle
Simó, Rafael
Rodríguez‐Gomez, Octavio
Ciudin, Andreea
Georges, Jean
Dumas, Annete
Maguire, Peggy
Krivec, David
Wimo, Anders
Valero, Sergi
Alegret, Montserrat
Jamilis, Laura
Zwan, Marissa
Sannemann, Lena
Arrufat, Jordi
Stomrud, Erik
Johansson, Gunilla
Shering, Craig
Glaysher, Bridget
Stewart, Neil
Belger, Mark
Iradier, Fatima
Campo, Laura
author_facet Boada, Mercè
Rodrigo, Adrián
Jessen, Frank
Wimblad, Bengt
Kramberger, Milica G.
Visser, Pieter Jelle
Simó, Rafael
Rodríguez‐Gomez, Octavio
Ciudin, Andreea
Georges, Jean
Dumas, Annete
Maguire, Peggy
Krivec, David
Wimo, Anders
Valero, Sergi
Alegret, Montserrat
Jamilis, Laura
Zwan, Marissa
Sannemann, Lena
Arrufat, Jordi
Stomrud, Erik
Johansson, Gunilla
Shering, Craig
Glaysher, Bridget
Stewart, Neil
Belger, Mark
Iradier, Fatima
Campo, Laura
author_sort Boada, Mercè
collection PubMed
description INTRODUCTION: The Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project was conceived to explore innovative complementary strategies to uncover hidden prodromal and mild Alzheimer's disease (AD) dementia cases and to raise awareness both in the general public and among health professionals about the importance of early diagnosis. METHODS: Four different strategies or RUNs were used: (a) a web‐based (WB) prescreening tool, (2) an open house initiative (OHI), (3) a primary care–based protocol for early detection of cognitive decline (PC), and (4) a tertiary care–based pre‐screening at diabetologist clinics (DC). RESULTS: A total of 1129 patients at high risk of having prodromal AD or dementia were identified of 2847 pre‐screened individuals (39.7%). The corresponding proportion for the different initiatives were 36.8% (WB), 35.6% (OHI), 44.4% (PC), and 58.3% (DC). CONCLUSION: These four complementary pre‐screening strategies were useful for identifying individuals at high risk of having prodromal or mild AD.
format Online
Article
Text
id pubmed-9290633
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-92906332022-07-20 Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project Boada, Mercè Rodrigo, Adrián Jessen, Frank Wimblad, Bengt Kramberger, Milica G. Visser, Pieter Jelle Simó, Rafael Rodríguez‐Gomez, Octavio Ciudin, Andreea Georges, Jean Dumas, Annete Maguire, Peggy Krivec, David Wimo, Anders Valero, Sergi Alegret, Montserrat Jamilis, Laura Zwan, Marissa Sannemann, Lena Arrufat, Jordi Stomrud, Erik Johansson, Gunilla Shering, Craig Glaysher, Bridget Stewart, Neil Belger, Mark Iradier, Fatima Campo, Laura Alzheimers Dement Featured Articles INTRODUCTION: The Models of Patient Engagement for Alzheimer's Disease (MOPEAD) project was conceived to explore innovative complementary strategies to uncover hidden prodromal and mild Alzheimer's disease (AD) dementia cases and to raise awareness both in the general public and among health professionals about the importance of early diagnosis. METHODS: Four different strategies or RUNs were used: (a) a web‐based (WB) prescreening tool, (2) an open house initiative (OHI), (3) a primary care–based protocol for early detection of cognitive decline (PC), and (4) a tertiary care–based pre‐screening at diabetologist clinics (DC). RESULTS: A total of 1129 patients at high risk of having prodromal AD or dementia were identified of 2847 pre‐screened individuals (39.7%). The corresponding proportion for the different initiatives were 36.8% (WB), 35.6% (OHI), 44.4% (PC), and 58.3% (DC). CONCLUSION: These four complementary pre‐screening strategies were useful for identifying individuals at high risk of having prodromal or mild AD. John Wiley and Sons Inc. 2021-07-26 2022-06 /pmc/articles/PMC9290633/ /pubmed/34310061 http://dx.doi.org/10.1002/alz.12441 Text en © 2021 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Featured Articles
Boada, Mercè
Rodrigo, Adrián
Jessen, Frank
Wimblad, Bengt
Kramberger, Milica G.
Visser, Pieter Jelle
Simó, Rafael
Rodríguez‐Gomez, Octavio
Ciudin, Andreea
Georges, Jean
Dumas, Annete
Maguire, Peggy
Krivec, David
Wimo, Anders
Valero, Sergi
Alegret, Montserrat
Jamilis, Laura
Zwan, Marissa
Sannemann, Lena
Arrufat, Jordi
Stomrud, Erik
Johansson, Gunilla
Shering, Craig
Glaysher, Bridget
Stewart, Neil
Belger, Mark
Iradier, Fatima
Campo, Laura
Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
title Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
title_full Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
title_fullStr Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
title_full_unstemmed Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
title_short Complementary pre‐screening strategies to uncover hidden prodromal and mild Alzheimer's disease: Results from the MOPEAD project
title_sort complementary pre‐screening strategies to uncover hidden prodromal and mild alzheimer's disease: results from the mopead project
topic Featured Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290633/
https://www.ncbi.nlm.nih.gov/pubmed/34310061
http://dx.doi.org/10.1002/alz.12441
work_keys_str_mv AT boadamerce complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT rodrigoadrian complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT jessenfrank complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT wimbladbengt complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT krambergermilicag complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT visserpieterjelle complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT simorafael complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT rodriguezgomezoctavio complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT ciudinandreea complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT georgesjean complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT dumasannete complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT maguirepeggy complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT krivecdavid complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT wimoanders complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT valerosergi complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT alegretmontserrat complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT jamilislaura complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT zwanmarissa complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT sannemannlena complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT arrufatjordi complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT stomruderik complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT johanssongunilla complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT sheringcraig complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT glaysherbridget complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT stewartneil complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT belgermark complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT iradierfatima complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT campolaura complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject
AT complementaryprescreeningstrategiestouncoverhiddenprodromalandmildalzheimersdiseaseresultsfromthemopeadproject