Cargando…

Sex differences in the neuropathological hallmarks of Alzheimer’s disease: focus on cognitively intact elderly individuals

AIMS: Women are more vulnerable to Alzheimer's disease (AD) than men. We investigated (i) whether and at what age the AD hallmarks, that is, β‐amyloid (Aβ) and hyperphosphorylated Tau (p‐Tau) show sex differences; and (ii) whether such sex differences may occur in cognitively intact elderly ind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Yu‐Ting, Boonstra, Jackson, McGurran, Hugo, Stormmesand, Jochem, Sluiter, Arja, Balesar, Rawien, Verwer, Ronald, Swaab, Dick, Bao, Ai‐Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9290663/ https://www.ncbi.nlm.nih.gov/pubmed/33969531 http://dx.doi.org/10.1111/nan.12729

Ejemplares similares

Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer’s disease and the potential role of local estrogens
por: Hu, Yu-Ting, et al.
Publicado: (2023)

Nigral neuropathology of Parkinson’s motor subtypes coincide with circuitopathies: a scoping review
por: Boonstra, Jackson Tyler, et al.
Publicado: (2022)

Increased pituitary adenylate cyclase-activating peptide genes expression in the prefrontal cortex in schizophrenia in relation to suicide
por: Slabe, Zala, et al.
Publicado: (2023)

Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients
por: Guo, Lei, et al.
Publicado: (2022)

Reduced Numbers of Corticotropin‐Releasing Hormone Neurons in Narcolepsy Type 1
por: Shan, Ling, et al.
Publicado: (2022)

Increased glutamic acid decarboxylase expression in the hypothalamic suprachiasmatic nucleus in depression
por: Wu, Xueyan, et al.
Publicado: (2017)

Sexually Dimorphic Changes of Hypocretin (Orexin) in Depression
por: Lu, Jing, et al.
Publicado: (2017)

Distinct proteomic profiles in prefrontal subareas of elderly major depressive disorder and bipolar disorder patients
por: Qi, Yang-Jian, et al.
Publicado: (2022)

Neural stem cells improve neuronal survival in cultured postmortem brain tissue from aged and Alzheimer patients
por: Wu, L, et al.
Publicado: (2008)

The functional microscopic neuroanatomy of the human subthalamic nucleus
por: Alkemade, Anneke, et al.
Publicado: (2019)

Neuropathology of stress
por: Lucassen, Paul J., et al.
Publicado: (2013)

Comparison of inpatient psychiatric medication management in gender diverse youth with cisgender peers
por: Carrillo, Nina, et al.
Publicado: (2023)

Neuropathological hallmarks of fetal hydrocephalus linked to CCDC88C pathogenic variants
por: Marguet, Florent, et al.
Publicado: (2021)

A unified 3D map of microscopic architecture and MRI of the human brain
por: Alkemade, Anneke, et al.
Publicado: (2022)

Neuropathological hallmarks in autopsied cases with mitochondrial diseases caused by the mitochondrial 3243A>G mutation
por: Miyahara, Hiroaki, et al.
Publicado: (2023)

The stress systems in depression: a postmortem study
por: Bao, Ai-Min, et al.
Publicado: (2014)

The human hypothalamus in mood disorders: The HPA axis in the center
por: Bao, Ai-Min, et al.
Publicado: (2018)

Dietary Spray-Dried Porcine Plasma Reduces Neuropathological Alzheimer’s Disease Hallmarks in SAMP8 Mice
por: Rosell-Cardona, Cristina, et al.
Publicado: (2021)

Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice
por: de Sousa, Diana M. Bessa, et al.
Publicado: (2023)

Olfactory neuropathology in Alzheimer’s disease: a sign of ongoing neurodegeneration
por: Son, Gowoon, et al.
Publicado: (2021)

Vulnerability and resilience to Alzheimer’s disease: early life conditions modulate neuropathology and determine cognitive reserve
por: Lesuis, Sylvie L., et al.
Publicado: (2018)

Sulfatide Deficiency, an Early Alzheimer’s Lipidomic Signature, Causes Brain Ventricular Enlargement in the Absence of Classical Neuropathological Hallmarks
por: Palavicini, Juan Pablo, et al.
Publicado: (2022)

Cell senescence in neuropathology: A focus on neurodegeneration and tumours
por: Carreno, Gabriela, et al.
Publicado: (2021)

Neuropathology of Parkinson’s disease after focused ultrasound thalamotomy
por: Koga, Shunsuke, et al.
Publicado: (2022)

Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State
por: Svensson, Bengt, et al.
Publicado: (2023)

Molecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State
por: Svensson, Bengt, et al.
Publicado: (2023)

Lamotrigine protects against cognitive deficits, synapse and nerve cell damage, and hallmark neuropathologies in a mouse model of Alzheimer’s disease
por: Fu, Xin-Xin, et al.
Publicado: (2022)

Hallmarks of cancer and hallmarks of aging
por: Blagosklonny, Mikhail V.
Publicado: (2022)

Vitamin K and Hallmarks of Ageing: Focus on Diet and Gut Microbiome
por: Dai, Lu, et al.
Publicado: (2023)

TREM2‐induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology
por: Fracassi, Anna, et al.
Publicado: (2022)

Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia
por: Selvaraji, Sharmelee, et al.
Publicado: (2022)

The Hallmarks of Aging: Leveraging on Their Interactions
por: Cuervo, Ana Maria, et al.
Publicado: (2021)

Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn(2+) in cognitively intact aged individuals with Alzheimer’s disease neuropathology
por: Bjorklund, Nicole L, et al.
Publicado: (2012)

The hallmarks of ovarian cancer: Focus on angiogenesis and micro-environment and new models for their characterisation
por: Heredia-Soto, V., et al.
Publicado: (2020)

Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction
por: van der Rijt, Sanne, et al.
Publicado: (2020)

Identification of a dihydropyridine scaffold that blocks ryanodine receptors
por: Gunaratne, Gihan S., et al.
Publicado: (2021)

Genetic and biological hallmarks of colorectal cancer
por: Li, Jiexi, et al.
Publicado: (2021)

Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development
por: Rabinovici, Gil D., et al.
Publicado: (2016)

The “hallmark” cells
por: Pandiar, Deepak, et al.
Publicado: (2019)

Hallmarks of ribosomopathies
por: Kampen, Kim R, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_skl76eilr2pldrri2nijm71ui3