Cargando…

Relationships between early age at onset of psychotic symptoms and treatment resistant schizophrenia

AIM: Early age at schizophrenia onset (EOS) has been associated with a worse clinical course, although previous studies reported substantial heterogeneity. Despite the relevance of the subject, the relationship between the age of onset and treatment resistant schizophrenia (TRS) is less clear. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iasevoli, Felice, Razzino, Eugenio, Altavilla, Benedetta, Avagliano, Camilla, Barone, Annarita, Ciccarelli, Mariateresa, D'Ambrosio, Luigi, Matrone, Marta, Milandri, Federica, Notar Francesco, Danilo, Fornaro, Michele, de Bartolomeis, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Publishing Asia Pty Ltd 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291026/ https://www.ncbi.nlm.nih.gov/pubmed/33998142 http://dx.doi.org/10.1111/eip.13174

Ejemplares similares

O9.4. RELATIONSHIPS BETWEEN AGE AT ONSET OF PSYCHOTIC SYMPTOMS AND POOR RESPONSE TO ANTIPSYCHOTICS IN A SAMPLE OF TRS/NON-TRS PATIENTS
por: Iasevoli, Felice, et al.
Publicado: (2020)

S202. PROXIMAL AND DISTAL FACTORS ASSOCIATED WITH CLOZAPINE EXPOSURE IN A SAMPLE OF TREATMENT RESISTANT AND TREATMENT RESPONSIVE SCHIZOPHRENIA PATIENTS
por: Barone, Annarita, et al.
Publicado: (2020)

S228. TOWARD EARLY DETECTION OF TREATMENT RESISTANT SCHIZOPHRENIA: PREDICTIVE INFORMATION ON NON-RESPONSE TO ANTIPSYCHOTICS BY EVALUATION OF A FEW CLINICAL FACTORS: A STUDY BY ROC CURVE ANALYSIS AND CONFIRMATORY MULTIVARIATE ANALYSIS
por: Iasevoli, Felice, et al.
Publicado: (2018)

F233. NEGATIVE SYMPTOMS ARE INDEPENDENT MODERATOR FACTORS OF TREATMENT RESISTANT SCHIZOPHRENIA EFFECTS ON MULTIPLE CLINICAL, PSYCHOPATHOLOGICAL, COGNITIVE AND PSYCHOSOCIAL VARIABLES
por: Iasevoli, Felice, et al.
Publicado: (2018)

Disease Severity in Treatment Resistant Schizophrenia Patients Is Mainly Affected by Negative Symptoms, Which Mediate the Effects of Cognitive Dysfunctions and Neurological Soft Signs
por: Iasevoli, Felice, et al.
Publicado: (2018)

T226. CLINICAL PREDICTORS OF FUNCTIONAL CAPACITY IN TREATMENT RESISTANT SCHIZOPHRENIA PATIENTS: COMPARISON WITH RESPONDER PATIENTS, ROLE OF NEGATIVE SYMPTOMS, PROBLEM SOLVING DYSFUNCTIONS, AND NEUROLOGICAL SOFT SIGNS
por: Iasevoli, Felice, et al.
Publicado: (2018)

M170. GENETIC CHARACTERIZATION OF A COHORT OF PATIENTS AFFECTED BY SCHIZOPHRENIA. THE ROLE FOR RARE STRUCTURAL VARIANTS IN MODULATING TREATMENT RESISTANT ENDOPHENOTYPES: PRELIMINARY DATA
por: Barone, Annarita, et al.
Publicado: (2020)

Dopamine Dynamics and Neurobiology of Non-Response to Antipsychotics, Relevance for Treatment Resistant Schizophrenia: A Systematic Review and Critical Appraisal
por: Iasevoli, Felice, et al.
Publicado: (2023)

M139. DIFFERENTIAL PATTERNS OF BRAIN METABOLISM IN STABILIZED, ACTIVELY SYMPTOMATIC TREATMENT RESISTANT VS. TREATMENT RESPONDER SCHIZOPHRENIA PATIENTS: A STUDY BY 18F-FDG-POSITRON EMISSION TOMOGRAPHY AND STRUCTURAL 3T MRI
por: Iasevoli, Felice, et al.
Publicado: (2020)

Linking Inflammation, Aberrant Glutamate-Dopamine Interaction, and Post-synaptic Changes: Translational Relevance for Schizophrenia and Antipsychotic Treatment: a Systematic Review
por: de Bartolomeis, Andrea, et al.
Publicado: (2022)

The Neurobiological Underpinnings of Obsessive-Compulsive Symptoms in Psychosis, Translational Issues for Treatment-Resistant Schizophrenia
por: Vellucci, Licia, et al.
Publicado: (2023)

Neural substrates of verbal memory impairment in schizophrenia: A multimodal connectomics study
por: Tranfa, Mario, et al.
Publicado: (2023)

The Effects of Antipsychotics on the Synaptic Plasticity Gene Homer1a Depend on a Combination of Their Receptor Profile, Dose, Duration of Treatment, and Brain Regions Targeted
por: Iasevoli, Felice, et al.
Publicado: (2020)

Schizophrenia Synaptic Pathology and Antipsychotic Treatment in the Framework of Oxidative and Mitochondrial Dysfunction: Translational Highlights for the Clinics and Treatment
por: De Simone, Giuseppe, et al.
Publicado: (2023)

Dysregulated Signaling at Postsynaptic Density: A Systematic Review and Translational Appraisal for the Pathophysiology, Clinics, and Antipsychotics’ Treatment of Schizophrenia
por: de Bartolomeis, Andrea, et al.
Publicado: (2023)

Canonical and Non-Canonical Antipsychotics’ Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia
por: de Bartolomeis, Andrea, et al.
Publicado: (2023)

Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia
por: de Bartolomeis, Andrea, et al.
Publicado: (2020)

S205. A TRANSLATIONAL HOMER 1A-BASED NETWORK APPROACH: IMAGING HOW HALOPERIDOL MODULATES GLUTAMATE SYSTEM FUNCTIONAL CONNECTIVITY
por: Vellucci, Licia, et al.
Publicado: (2020)

Antipsychotics-Induced Changes in Synaptic Architecture and Functional Connectivity: Translational Implications for Treatment Response and Resistance
por: de Bartolomeis, Andrea, et al.
Publicado: (2022)

F234. TYPICAL AND ATYPICAL ANTIPSYCHOTICS’ D2R AFFINITY AND DOSES INFLUENCES POSTSYNAPTIC DENSITY BY MODULATING THE SPATIAL EXPRESSION OF HOMER1A A GENE HIGHLY IMPLICATED IN SYNAPTIC PLASTICITY AND PSYCHOSIS
por: Camilla, Avagliano, et al.
Publicado: (2018)

The Glutamatergic Aspects of Schizophrenia Molecular Pathophysiology: Role of the Postsynaptic Density, and Implications for Treatment
por: Iasevoli, Felice, et al.
Publicado: (2014)

Tobacco smoking in treatment-resistant schizophrenia patients is associated with impaired cognitive functioning, more severe negative symptoms, and poorer social adjustment
por: Iasevoli, Felice, et al.
Publicado: (2013)

Insulin effects on core neurotransmitter pathways involved in schizophrenia neurobiology: a meta-analysis of preclinical studies. Implications for the treatment
por: de Bartolomeis, Andrea, et al.
Publicado: (2023)

A Postsynaptic Density Immediate Early Gene-Based Connectome Analysis of Acute NMDAR Blockade and Reversal Effect of Antipsychotic Administration
por: Barone, Annarita, et al.
Publicado: (2023)

PM437. Spatial and temporal modulation of Homer1a gene expression at the post-synaptic density is related to D2R affinity and dose of antipsychotics: translational considerations for schizophrenia treatment strategies.
por: de Bartolomeis, Andrea, et al.
Publicado: (2016)

Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism
por: de Bartolomeis, Andrea, et al.
Publicado: (2015)

Predictors of Treatment Resistance Across Different Clinical Subtypes of Depression: Comparison of Unipolar vs. Bipolar Cases
por: Fornaro, Michele, et al.
Publicado: (2020)

Psychological distress in patients with serious mental illness during the COVID-19 outbreak and one-month mass quarantine in Italy
por: Iasevoli, Felice, et al.
Publicado: (2020)

Rational and Translational Implications of D-Amino Acids for Treatment-Resistant Schizophrenia: From Neurobiology to the Clinics
por: de Bartolomeis, Andrea, et al.
Publicado: (2022)

Efficacy and Clinical Determinants of Antipsychotic Polypharmacy in Psychotic Patients Experiencing an Acute Relapse and Admitted to Hospital Stay: Results from a Cross-Sectional and a Subsequent Longitudinal Pilot Study
por: Iasevoli, Felice, et al.
Publicado: (2014)

Predicting the Severity of Lockdown-Induced Psychiatric Symptoms with Machine Learning
por: D’Urso, Giordano, et al.
Publicado: (2022)

Lurasidone in the Treatment of Bipolar Depression: Systematic Review of Systematic Reviews
por: Fornaro, Michele, et al.
Publicado: (2017)

Does the “Silver Bullet” Lose its Shine Over the Time? Assessment of Loss of Lithium Response in a Preliminary Sample of Bipolar Disorder Outpatients
por: Fornaro, M., et al.
Publicado: (2016)

Treatment-Resistant to Antipsychotics: A Resistance to Everything? Psychotherapy in Treatment-Resistant Schizophrenia and Nonaffective Psychosis: A 25-Year Systematic Review and Exploratory Meta-Analysis
por: Polese, Daniela, et al.
Publicado: (2019)

Editorial: Neurobiology, Clinical Course, and Therapeutic Approaches of Treatment-Resistant Schizophrenia: Toward an Integrated View
por: Iasevoli, Felice, et al.
Publicado: (2019)

Treating the Synapse in Major Psychiatric Disorders: The Role of Postsynaptic Density Network in Dopamine-Glutamate Interplay and Psychopharmacologic Drugs Molecular Actions
por: Tomasetti, Carmine, et al.
Publicado: (2017)

The effects of sustained COVID‐19 emergency and restrictions on the mental health of subjects with serious mental illness: A prospective study
por: Barone, Annarita, et al.
Publicado: (2022)

Immediate-Early Genes Modulation by Antipsychotics: Translational Implications for a Putative Gateway to Drug-Induced Long-Term Brain Changes
por: de Bartolomeis, Andrea, et al.
Publicado: (2017)

Speech-on-speech masking and psychotic symptoms in schizophrenia
por: Wu, Chao, et al.
Publicado: (2018)

Schizophrenia, Not a Psychotic Disorder: Bleuler Revisited
por: Loch, Alexandre Andrade
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qp5jtr5eflg70rluc5i8v03ulh