Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta‐regression analysis to develop an enrichment strategy

BACKGROUND: There is considerable unexplained variability in alcohol abstinence rates (AR) in the placebo groups of randomized controlled trials (RCTs) for alcohol dependence (AD). This is of particular interest because placebo responses correlate negatively with treatment effect size. Recent eviden...

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Detalles Bibliográficos
Autores principales: Scherrer, Bruno, Guiraud, Julien, Addolorato, Giovanni, Aubin, Henri‐Jean, de Bejczy, Andrea, Benyamina, Amine, van den Brink, Wim, Caputo, Fabio, Dematteis, Maurice, Goudriaan, Anna E., Gual, Antoni, Kiefer, Falk, Leggio, Lorenzo, Lesch, Otto‐Michael, Maremmani, Icro, Nutt, David J., Paille, François, Perney, Pascal, Poulnais, Roch, Raffaillac, Quentin, Rehm, Jürgen, Rolland, Benjamin, Simon, Nicolas, Söderpalm, Bo, Sommer, Wolfgang H., Walter, Henriette, Spanagel, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291112/
https://www.ncbi.nlm.nih.gov/pubmed/34418121
http://dx.doi.org/10.1111/acer.14670

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