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Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
INTRODUCTION: Transcatheter mitral valve replacement (TMVR) is indicated in case of degenerated bioprosthesis in high‐risk patients. However, durability of these valves still represents an important issue. METHODS: Early severe structural valve deterioration of a mitral porcine surgical bioprosthesi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291126/ https://www.ncbi.nlm.nih.gov/pubmed/34386994 http://dx.doi.org/10.1111/jocs.15912 |
Sumario: | INTRODUCTION: Transcatheter mitral valve replacement (TMVR) is indicated in case of degenerated bioprosthesis in high‐risk patients. However, durability of these valves still represents an important issue. METHODS: Early severe structural valve deterioration of a mitral porcine surgical bioprosthesis and of a subsequent bovine TMVR, both at 4 years follow‐up, is here presented. RESULTS: Gross, histopathologic, and X‐ray examination revealed massive calcification of both devices and fibrous tissue overgrowth involving the TMVR stent. CONCLUSIONS: Careful clinical evaluation and strict follow‐up are mandatory to identify early signs of dysfunction and to intervene in a timely manner. |
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