Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses

INTRODUCTION: Transcatheter mitral valve replacement (TMVR) is indicated in case of degenerated bioprosthesis in high‐risk patients. However, durability of these valves still represents an important issue. METHODS: Early severe structural valve deterioration of a mitral porcine surgical bioprosthesi...

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Autores principales: Tessari, Chiara, Della Barbera, Mila, D'Onofrio, Augusto, Rubino, Maurizio, Gerosa, Gino, Basso, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291126/
https://www.ncbi.nlm.nih.gov/pubmed/34386994
http://dx.doi.org/10.1111/jocs.15912
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author Tessari, Chiara
Della Barbera, Mila
D'Onofrio, Augusto
Rubino, Maurizio
Gerosa, Gino
Basso, Cristina
author_facet Tessari, Chiara
Della Barbera, Mila
D'Onofrio, Augusto
Rubino, Maurizio
Gerosa, Gino
Basso, Cristina
author_sort Tessari, Chiara
collection PubMed
description INTRODUCTION: Transcatheter mitral valve replacement (TMVR) is indicated in case of degenerated bioprosthesis in high‐risk patients. However, durability of these valves still represents an important issue. METHODS: Early severe structural valve deterioration of a mitral porcine surgical bioprosthesis and of a subsequent bovine TMVR, both at 4 years follow‐up, is here presented. RESULTS: Gross, histopathologic, and X‐ray examination revealed massive calcification of both devices and fibrous tissue overgrowth involving the TMVR stent. CONCLUSIONS: Careful clinical evaluation and strict follow‐up are mandatory to identify early signs of dysfunction and to intervene in a timely manner.
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spelling pubmed-92911262022-07-20 Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses Tessari, Chiara Della Barbera, Mila D'Onofrio, Augusto Rubino, Maurizio Gerosa, Gino Basso, Cristina J Card Surg Case Reports INTRODUCTION: Transcatheter mitral valve replacement (TMVR) is indicated in case of degenerated bioprosthesis in high‐risk patients. However, durability of these valves still represents an important issue. METHODS: Early severe structural valve deterioration of a mitral porcine surgical bioprosthesis and of a subsequent bovine TMVR, both at 4 years follow‐up, is here presented. RESULTS: Gross, histopathologic, and X‐ray examination revealed massive calcification of both devices and fibrous tissue overgrowth involving the TMVR stent. CONCLUSIONS: Careful clinical evaluation and strict follow‐up are mandatory to identify early signs of dysfunction and to intervene in a timely manner. John Wiley and Sons Inc. 2021-08-12 2021-11 /pmc/articles/PMC9291126/ /pubmed/34386994 http://dx.doi.org/10.1111/jocs.15912 Text en © 2021 The Authors. Journal of Cardiac Surgery published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Tessari, Chiara
Della Barbera, Mila
D'Onofrio, Augusto
Rubino, Maurizio
Gerosa, Gino
Basso, Cristina
Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
title Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
title_full Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
title_fullStr Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
title_full_unstemmed Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
title_short Clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
title_sort clinicopathological insights from early structural valve deterioration of a surgical and transcatheter valve‐in‐valve mitral bioprotheses
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291126/
https://www.ncbi.nlm.nih.gov/pubmed/34386994
http://dx.doi.org/10.1111/jocs.15912
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