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Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus
BACKGROUND: Interleukin (IL)‐31 is a cytokine involved in allergic inflammation which induces pruritus across species including dogs. Using recombinant canine IL‐31 we have developed a model of pruritus in the dog to evaluate onset of action and duration of effect of therapeutic drugs. OBJECTIVE: To...
Autores principales: | Fleck, Timothy J., Norris, Lori R., Mahabir, Sean, Walters, Rodney R., Martinon, Olivier, Dunham, Steven A., Gonzales, Andrea J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291138/ https://www.ncbi.nlm.nih.gov/pubmed/33830571 http://dx.doi.org/10.1111/vde.12943 |
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