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Methionine oxidation of proteins analyzed by affinity capillary electrophoresis in presence of silver(I) and gold(III) ions
Oxidative damage of biopharmaceuticals during manufacturing and storage is a key concern throughout pharmaceutical development. However, few simple and robust analytical methods are available for the determination of oxidation sites. Here, the potential of affinity capillary electrophoresis (ACE) in...
Autores principales: | Hutanu, Andrei, Hauser, Peter C., Moritz, Bernd, Kiessig, Steffen, Noël, Aurélie, Stracke, Jan O., Wild, Markus, Schwarz, Maria A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291207/ https://www.ncbi.nlm.nih.gov/pubmed/33651405 http://dx.doi.org/10.1002/elps.202000355 |
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