Multiple epitopes of hepatitis B virus surface antigen targeted by human plasma‐derived immunoglobulins coincide with clinically observed escape mutations

Hepatitis B immune globulin (HBIG) is a human plasma‐derived immunoglobulin G concentrate that contains a high titer of neutralizing antibodies (anti‐HBs) to the hepatitis B virus (HBV) surface antigen (HBsAg). HBIG is known to be highly effective in treating HBV infections, however, a more systemat...

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Detalles Bibliográficos
Autores principales: Tarafdar, Sreya, Virata, Maria Luisa, Yan, Hailing, Zhong, Lilin, Deng, Lu, Xu, Yanqun, He, Yong, Struble, Evi, Zhang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291308/
https://www.ncbi.nlm.nih.gov/pubmed/34406663
http://dx.doi.org/10.1002/jmv.27278

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