Multi-Objective Drug Design Based on Graph-Fragment Molecular Representation and Deep Evolutionary Learning

Drug discovery is a challenging process with a huge molecular space to be explored and numerous pharmacological properties to be appropriately considered. Among various drug design protocols, fragment-based drug design is an effective way of constraining the search space and better utilizing biologi...

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Detalles Bibliográficos
Autores principales: Mukaidaisi, Muhetaer, Vu, Andrew, Grantham, Karl, Tchagang, Alain, Li, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291509/
https://www.ncbi.nlm.nih.gov/pubmed/35860028
http://dx.doi.org/10.3389/fphar.2022.920747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291509/
https://www.ncbi.nlm.nih.gov/pubmed/35860028
http://dx.doi.org/10.3389/fphar.2022.920747

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