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Epimedin C Alleviates Glucocorticoid-Induced Suppression of Osteogenic Differentiation by Modulating PI3K/AKT/RUNX2 Signaling Pathway

Secondary osteoporosis is triggered mostly by glucocorticoid (GC) therapy. Dexamethasone (DEX) was reported to inhibit osteogenic differentiation in zebrafish larvae and MC3T3-E1 cells in prior research. In this research, we primarily examined the protective impacts of epimedin C on the osteogenic i...

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Detalles Bibliográficos
Autores principales: Xu, Yongxiang, Chen, Shichun, Huang, Linxuan, Han, Weichao, Shao, Yingying, Chen, Minyi, Zhang, Yusheng, He, Ruirong, Xie, Baocheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291512/
https://www.ncbi.nlm.nih.gov/pubmed/35860032
http://dx.doi.org/10.3389/fphar.2022.894832