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Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model
A solution for challenging hip dysplasia surgery could be a patient‐specific 3D‐printed shelf implant that is positioned extra‐articular and restores the dysplastic acetabular rim to normal anatomical dimensions. The anatomical correction and biomechanical stability of this concept were tested in a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291530/ https://www.ncbi.nlm.nih.gov/pubmed/34191341 http://dx.doi.org/10.1002/jor.25133 |
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author | Willemsen, Koen Tryfonidou, Marianna Sakkers, Ralph Castelein, René M. Zadpoor, Amir A. Seevinck, Peter Weinans, Harrie Meij, Björn van der Wal, Bart C. H. |
author_facet | Willemsen, Koen Tryfonidou, Marianna Sakkers, Ralph Castelein, René M. Zadpoor, Amir A. Seevinck, Peter Weinans, Harrie Meij, Björn van der Wal, Bart C. H. |
author_sort | Willemsen, Koen |
collection | PubMed |
description | A solution for challenging hip dysplasia surgery could be a patient‐specific 3D‐printed shelf implant that is positioned extra‐articular and restores the dysplastic acetabular rim to normal anatomical dimensions. The anatomical correction and biomechanical stability of this concept were tested in a canine model that, like humans, also suffers from hip dysplasia. Using 3D reconstructed computed tomography images the 3D shelf implant was designed to restore the radiological dysplastic hip parameters to healthy parameters. It was tested ex vivo on three dog cadavers (six hips) with hip dysplasia. Each hip was subjected to a biomechanical subluxation test, first without and then with the 3D shelf implant in place. Subsequently, an implant failure test was performed to test the primary implant fixation. At baseline, the dysplastic hips had an average Norberg angle of 88 ± 3° and acetabular coverage of 47 ± 2% and subluxated at an average of 83 ± 2° of femoral adduction. After adding the patient‐specific shelf implants the dysplastic hips had an average Norberg angle of 122 ± 2° and acetabular coverage of 67 ± 3% and subluxated at an average of 117 ± 2° of femoral adduction. Implant failure after primary implant fixation occurred at an average of 1330 ± 320 Newton. This showed that the patient‐specific shelf implants significantly improved the coverage and stability of dysplastic hips in a canine model with naturally occurring hip dysplasia. The 3D shelf is a promising concept for treating residual hip dysplasia with a straightforward technology‐driven approach; however, the clinical safety needs to be further investigated in an experimental proof‐of‐concept animal study. |
format | Online Article Text |
id | pubmed-9291530 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92915302022-07-20 Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model Willemsen, Koen Tryfonidou, Marianna Sakkers, Ralph Castelein, René M. Zadpoor, Amir A. Seevinck, Peter Weinans, Harrie Meij, Björn van der Wal, Bart C. H. J Orthop Res Research Articles A solution for challenging hip dysplasia surgery could be a patient‐specific 3D‐printed shelf implant that is positioned extra‐articular and restores the dysplastic acetabular rim to normal anatomical dimensions. The anatomical correction and biomechanical stability of this concept were tested in a canine model that, like humans, also suffers from hip dysplasia. Using 3D reconstructed computed tomography images the 3D shelf implant was designed to restore the radiological dysplastic hip parameters to healthy parameters. It was tested ex vivo on three dog cadavers (six hips) with hip dysplasia. Each hip was subjected to a biomechanical subluxation test, first without and then with the 3D shelf implant in place. Subsequently, an implant failure test was performed to test the primary implant fixation. At baseline, the dysplastic hips had an average Norberg angle of 88 ± 3° and acetabular coverage of 47 ± 2% and subluxated at an average of 83 ± 2° of femoral adduction. After adding the patient‐specific shelf implants the dysplastic hips had an average Norberg angle of 122 ± 2° and acetabular coverage of 67 ± 3% and subluxated at an average of 117 ± 2° of femoral adduction. Implant failure after primary implant fixation occurred at an average of 1330 ± 320 Newton. This showed that the patient‐specific shelf implants significantly improved the coverage and stability of dysplastic hips in a canine model with naturally occurring hip dysplasia. The 3D shelf is a promising concept for treating residual hip dysplasia with a straightforward technology‐driven approach; however, the clinical safety needs to be further investigated in an experimental proof‐of‐concept animal study. John Wiley and Sons Inc. 2021-07-14 2022-05 /pmc/articles/PMC9291530/ /pubmed/34191341 http://dx.doi.org/10.1002/jor.25133 Text en © 2021 The Authors. Journal of Orthopaedic Research ® published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Articles Willemsen, Koen Tryfonidou, Marianna Sakkers, Ralph Castelein, René M. Zadpoor, Amir A. Seevinck, Peter Weinans, Harrie Meij, Björn van der Wal, Bart C. H. Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model |
title | Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model |
title_full | Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model |
title_fullStr | Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model |
title_full_unstemmed | Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model |
title_short | Patient‐specific 3D‐printed shelf implant for the treatment of hip dysplasia: Anatomical and biomechanical outcomes in a canine model |
title_sort | patient‐specific 3d‐printed shelf implant for the treatment of hip dysplasia: anatomical and biomechanical outcomes in a canine model |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291530/ https://www.ncbi.nlm.nih.gov/pubmed/34191341 http://dx.doi.org/10.1002/jor.25133 |
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