Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field

The early differential diagnosis of Parkinson disease and atypical parkinsonism is a major challenge. The use of single photon emission computed tomography (SPECT)/positron emission tomography (PET) molecular imaging to investigate parkinsonism is a fast‐developing field. Imaging biomarker research...

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Detalles Bibliográficos
Autores principales: Verger, Antoine, Grimaldi, Stephan, Ribeiro, Maria‐Joao, Frismand, Solène, Guedj, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291534/
https://www.ncbi.nlm.nih.gov/pubmed/34338333
http://dx.doi.org/10.1002/ana.26187
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author Verger, Antoine
Grimaldi, Stephan
Ribeiro, Maria‐Joao
Frismand, Solène
Guedj, Eric
author_facet Verger, Antoine
Grimaldi, Stephan
Ribeiro, Maria‐Joao
Frismand, Solène
Guedj, Eric
author_sort Verger, Antoine
collection PubMed
description The early differential diagnosis of Parkinson disease and atypical parkinsonism is a major challenge. The use of single photon emission computed tomography (SPECT)/positron emission tomography (PET) molecular imaging to investigate parkinsonism is a fast‐developing field. Imaging biomarker research may potentially lead to more accurate disease detection, enabling earlier diagnosis and treatment. This review summarizes recent SPECT/PET advances in radiopharmaceuticals and imaging technologies/analyses that improve the diagnosis of neurodegenerative parkinsonism. We are currently witnessing a turning point in the field. Integrating molecular imaging as a diagnostic technique represents an opportunity to reassess the strategies for diagnosing neurodegenerative parkinsonism. ANN NEUROL 2021;90:711–719
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spelling pubmed-92915342022-07-20 Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field Verger, Antoine Grimaldi, Stephan Ribeiro, Maria‐Joao Frismand, Solène Guedj, Eric Ann Neurol Review The early differential diagnosis of Parkinson disease and atypical parkinsonism is a major challenge. The use of single photon emission computed tomography (SPECT)/positron emission tomography (PET) molecular imaging to investigate parkinsonism is a fast‐developing field. Imaging biomarker research may potentially lead to more accurate disease detection, enabling earlier diagnosis and treatment. This review summarizes recent SPECT/PET advances in radiopharmaceuticals and imaging technologies/analyses that improve the diagnosis of neurodegenerative parkinsonism. We are currently witnessing a turning point in the field. Integrating molecular imaging as a diagnostic technique represents an opportunity to reassess the strategies for diagnosing neurodegenerative parkinsonism. ANN NEUROL 2021;90:711–719 John Wiley & Sons, Inc. 2021-08-27 2021-11 /pmc/articles/PMC9291534/ /pubmed/34338333 http://dx.doi.org/10.1002/ana.26187 Text en © 2021 The Authors. Annals of Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review
Verger, Antoine
Grimaldi, Stephan
Ribeiro, Maria‐Joao
Frismand, Solène
Guedj, Eric
Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
title Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
title_full Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
title_fullStr Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
title_full_unstemmed Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
title_short Single Photon Emission Computed Tomography/Positron Emission Tomography Molecular Imaging for Parkinsonism: A Fast‐Developing Field
title_sort single photon emission computed tomography/positron emission tomography molecular imaging for parkinsonism: a fast‐developing field
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291534/
https://www.ncbi.nlm.nih.gov/pubmed/34338333
http://dx.doi.org/10.1002/ana.26187
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