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Colon fibroblasts from Pirc rats (F344/NTac‐Apc (am1137)) exhibit a proliferative and inflammatory phenotype that could support early stages of colon carcinogenesis

The role of fibroblast APC mutation in carcinogenesis is not clear. Apc (+/−) colon fibroblasts have been previously characterized: however, little is known about their behavior at very early‐stage of colon carcinogenesis. We cultured colon mucosa fibroblasts (PCF, Apc (+/−)) of Pirc rats (F344/NTac...

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Detalles Bibliográficos
Autores principales:	Tortora, Katia, Margheri, Francesca, Luceri, Cristina, Mocali, Alessandra, Ristori, Sara, Magnelli, Lucia, Caderni, Giovanna, Giovannelli, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Tumor Immunology and Microenvironment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291568/ https://www.ncbi.nlm.nih.gov/pubmed/34486752 http://dx.doi.org/10.1002/ijc.33796

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