Targeting stearoyl-coa desaturase enhances radiation induced ferroptosis and immunogenic cell death in esophageal squamous cell carcinoma

Overcoming resistance to radiation is a major challenge in cancer treatment. Stearoyl-coa desaturase (SCD1) is the enzyme responsible for oleic acid (OA) and palmitoleic acid (POA) formation. Here, we provided evidence that targeting SCD1 was capable of inducing ferroptosis and immunogenic cell deat...

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Detalles Bibliográficos
Autores principales: Luo, Hui, Wang, Xiaohui, Song, Shuai, Wang, Yunhan, Dan, Qinfu, Ge, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291654/
https://www.ncbi.nlm.nih.gov/pubmed/35859734
http://dx.doi.org/10.1080/2162402X.2022.2101769

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