Cargando…

Species-dependent impact of immunosuppressive squalene-gusperimus nanoparticles and adipose-derived stem cells on isolated human and rat pancreatic islets

Transplantation of pancreatic islets is a promising approach to controlling glucose levels in type 1 diabetes mellitus (T1DM), but islet survival is still limited. To overcome this, islet co-culture with mesenchymal stromal cells (MSCs) together with safe immunosuppressive agents like squalene-guspe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Navarro Chica, Carlos E., Qin, Tian, Pinheiro-Machado, Erika, de Haan, Bart J., Faas, M.M., Smink, Alexandra M., Sierra, Ligia, López, Betty L., de Vos, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291694/ https://www.ncbi.nlm.nih.gov/pubmed/35838041 http://dx.doi.org/10.1080/19382014.2022.2100191

Ejemplares similares

Toward Engineering a Novel Transplantation Site for Human Pancreatic Islets
por: Smink, Alexandra M., et al.
Publicado: (2013)

Enzymes for Pancreatic Islet Isolation Impact Chemokine-Production and Polarization of Insulin-Producing β-Cells with Reduced Functional Survival of Immunoisolated Rat Islet-Allografts as a Consequence
por: de Vos, Paul, et al.
Publicado: (2016)

Stimulation of vascularization of a subcutaneous scaffold applicable for pancreatic islet‐transplantation enhances immediate post‐transplant islet graft function but not long‐term normoglycemia
por: Smink, Alexandra M., et al.
Publicado: (2017)

Successful Islet Transplantation Into a Subcutaneous Polycaprolactone Scaffold in Mice and Pigs
por: Smink, Alexandra M., et al.
Publicado: (2022)

Therapeutic Strategies for Modulating the Extracellular Matrix to Improve Pancreatic Islet Function and Survival After Transplantation
por: Smink, Alexandra M., et al.
Publicado: (2018)

DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1
por: Paredes-Juarez, Genaro A., et al.
Publicado: (2015)

Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets
por: Llacua, L. Alberto, et al.
Publicado: (2018)

Towards standardization of human adipose-derived stromal cells secretomes
por: Pinheiro-Machado, Erika, et al.
Publicado: (2023)

Functional characterization of squalene synthase and squalene epoxidase in Taraxacum koksaghyz
por: Unland, Kristina, et al.
Publicado: (2018)

Functional diversity in Dichomitus squalens monokaryons
por: Casado López, Sara, et al.
Publicado: (2017)

Accumulation of Squalene in a Microalga Chlamydomonas reinhardtii by Genetic Modification of Squalene Synthase and Squalene Epoxidase Genes
por: Kajikawa, Masataka, et al.
Publicado: (2015)

Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress
por: Hu, Shuxian, et al.
Publicado: (2020)

Collagen type VI interaction improves human islet survival in immunoisolating microcapsules for treatment of diabetes
por: Llacua, L. Alberto, et al.
Publicado: (2018)

A Technology Platform to Test the Efficacy of Purification of Alginate
por: Paredes-Juarez, Genaro A., et al.
Publicado: (2014)

Surface Properties of Squalene/Meibum Films and NMR Confirmation of Squalene in Tears
por: Ivanova, Slavyana, et al.
Publicado: (2015)

Production of Squalene in Bacillus subtilis by Squalene Synthase Screening and Metabolic Engineering
por: Song, Yafeng, et al.
Publicado: (2020)

Identification of TLR2/TLR6 signalling lactic acid bacteria for supporting immune regulation
por: Ren, Chengcheng, et al.
Publicado: (2016)

Squalene through Its Post-Squalene Metabolites Is a Modulator of Hepatic Transcriptome in Rabbits
por: Abuobeid, Roubi, et al.
Publicado: (2022)

TLR2 and TLR4 activity in monocytes and macrophages after exposure to amoxicillin, ciprofloxacin, doxycycline and erythromycin
por: Silva Lagos, Luis, et al.
Publicado: (2022)

Immunological dynamics after subcutaneous immunization with a squalene‐based oil‐in‐water adjuvant
por: Schetters, Sjoerd T. T., et al.
Publicado: (2020)

Discovery of non-squalene triterpenes
por: Tao, Hui, et al.
Publicado: (2022)

Diffusion of Squalene in Nonaqueous Solvents
por: Kowert, Bruce A.
Publicado: (2022)

Oxidation of squalene by singlet oxygen and free radicals results in different compositions of squalene monohydroperoxide isomers
por: Shimizu, Naoki, et al.
Publicado: (2018)

Pancreatic Beta-Cell Purification by Altering FAD and NAD(P)H Metabolism
por: Smelt, M. J., et al.
Publicado: (2008)

Changes in intestinal gene expression and microbiota composition during late pregnancy are mouse strain dependent
por: Elderman, Marlies, et al.
Publicado: (2018)

Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
por: Hull, Claire M, et al.
Publicado: (2014)

L. plantarum WCFS1 enhances Treg frequencies by activating DCs even in absence of sampling of bacteria in the Peyer Patches
por: Bermudez-Brito, Miriam, et al.
Publicado: (2018)

Recent advances in the microbial production of squalene
por: Paramasivan, Kalaivani, et al.
Publicado: (2022)

Investigation of the Formation of Squalene Oligomers Exposed to Ultraviolet Light and Changes in the Exposed Squalene as a Potential Skin Model
por: Zecchini, Matteo, et al.
Publicado: (2022)

Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner
por: Elderman, Marlies, et al.
Publicado: (2016)

Determination of squalene in edible oils by transmethylation and GC analysis
por: Budge, Suzanne M., et al.
Publicado: (2018)

Caprine pancreatic islet xenotransplantation into diabetic immunosuppressed BALB/c mice
por: Hani, Homayoun, et al.
Publicado: (2014)

Squalene Synthase As a Target for Chagas Disease Therapeutics
por: Shang, Na, et al.
Publicado: (2014)

Introduction of a green algal squalene synthase enhances squalene accumulation in a strain of Synechocystis sp. PCC 6803
por: Pattanaik, Bagmi, et al.
Publicado: (2020)

Production of Squalene in Synechocystis sp. PCC 6803
por: Englund, Elias, et al.
Publicado: (2014)

Bacteria Do It Differently: An Alternative Path to Squalene
por: van der Donk, Wilfred A.
Publicado: (2015)

Solvent-Free Chemoselective Hydrogenation of Squalene to Squalane
por: Pandarus, Valerica, et al.
Publicado: (2017)

Squalene Emulsions for Parenteral Vaccine and Drug Delivery
por: Fox, Christopher B.
Publicado: (2009)

Positive Selection of Squalene Synthase in Cucurbitaceae Plants
por: Qian, Jieying, et al.
Publicado: (2019)

Strategies to Better Target Fungal Squalene Monooxygenase
por: Sagatova, Alia A.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j114a08p5b6gi0ci89l5ub8ubq