Disulfiram ameliorates ischemia/reperfusion-induced acute kidney injury by suppressing the caspase-11-GSDMD pathway

Acute kidney injury (AKI) is a serious condition with high mortality. The most common cause is kidney ischemia/reperfusion (IR) injury, which is thought to be closely related to pyroptosis. Disulfiram is a well-known alcohol abuse drug, and recent studies have shown its ability to mitigate pyroptosi...

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Detalles Bibliográficos
Autores principales: Cai, Qiaoting, Sun, Zhaoxing, Xu, Sujuan, Jiao, Xiaoyan, Guo, Shulan, Li, Yingxiang, Wu, Huan, Yu, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291718/
https://www.ncbi.nlm.nih.gov/pubmed/35837696
http://dx.doi.org/10.1080/0886022X.2022.2098764

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