Cargando…
The [1,2,4]Triazolo[4,3‐a]pyridine as a New Player in the Field of IDO1 Catalytic Holo‐Inhibitors
Inhibitors of indoleamine 2,3‐dioxygenase 1 (IDO1) are considered a promising strategy in cancer immunotherapy as they are able to boost the immune response and to work in synergy with other immunotherapeutic agents. Despite the fact that no IDO1 inhibitor has been approved so far, recent studies ha...
Autores principales: | Fallarini, Silvia, Bhela, Irene P., Aprile, Silvio, Torre, Enza, Ranza, Alice, Orecchini, Elena, Panfili, Eleonora, Pallotta, Maria T., Massarotti, Alberto, Serafini, Marta, Pirali, Tracey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291769/ https://www.ncbi.nlm.nih.gov/pubmed/34355531 http://dx.doi.org/10.1002/cmdc.202100446 |
Ejemplares similares
-
Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors
por: Serafini, Marta, et al.
Publicado: (2019) -
The Structural and Optical Properties of 1,2,4-Triazolo[4,3-a]pyridine-3-amine
por: Dymińska, Lucyna, et al.
Publicado: (2022) -
2-Methyl-1,2,4-triazolo[4,3-a]pyridin-2-ium tetrafluoroborate
por: Wei, Siping, et al.
Publicado: (2013) -
1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically
Stable Modulators of Store-Operated Calcium Entry
por: Aprile, Silvio, et al.
Publicado: (2021) -
Synthesis, biological activity and molecular modeling study of novel 1,2,4-triazolo[4,3-b][1,2,4,5]tetrazines and 1,2,4-triazolo[4,3-b][1,2,4]triazines
por: El-Reedy, Ahmed A. M., et al.
Publicado: (2020)