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Plasma neurofilament light chain concentrations as a biomarker of clinical and radiologic outcomes in relapsing multiple sclerosis: Post hoc analysis of Phase 3 ozanimod trials

BACKGROUND AND PURPOSE: We investigated plasma neurofilament light chain concentration (pNfL) as a biomarker for neuroaxonal damage and disease activity using data from Phase 3 trials of ozanimod in relapsing multiple sclerosis (RMS). METHODS: pNfL was measured before and after ozanimod 0.46 mg or 0...

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Detalles Bibliográficos
Autores principales:	Harris, Sarah, Comi, Giancarlo, Cree, Bruce A. C., Arnold, Douglas L., Steinman, Lawrence, Sheffield, James K., Southworth, Harry, Kappos, Ludwig, Cohen, Jeffrey A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Multiple Sclerosis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291872/ https://www.ncbi.nlm.nih.gov/pubmed/34292643 http://dx.doi.org/10.1111/ene.15009

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