RORγt inhibitor SR1001 alleviates acute pancreatitis by suppressing pancreatic IL‐17‐producing Th17 and γδ‐T cells in mice with ceruletide‐induced pancreatitis

The management of acute pancreatitis (AP) remains a challenge to clinicians worldwide for limited effective interventions. Retinoid orphan receptor gamma t (RORγt) is a therapeutic target for several diseases; however, it is unclear whether inhibiting RORγt can ameliorate AP. The relative expression...

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Detalles Bibliográficos
Autores principales: Wang, Jianfa, Xu, Yayun, Jing, Hui, Chang, Qimeng, Wu, Xubo, Zhang, Ziping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Basic Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291878/
https://www.ncbi.nlm.nih.gov/pubmed/34384137
http://dx.doi.org/10.1111/bcpt.13642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291878/
https://www.ncbi.nlm.nih.gov/pubmed/34384137
http://dx.doi.org/10.1111/bcpt.13642

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