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RORγt inhibitor SR1001 alleviates acute pancreatitis by suppressing pancreatic IL‐17‐producing Th17 and γδ‐T cells in mice with ceruletide‐induced pancreatitis
The management of acute pancreatitis (AP) remains a challenge to clinicians worldwide for limited effective interventions. Retinoid orphan receptor gamma t (RORγt) is a therapeutic target for several diseases; however, it is unclear whether inhibiting RORγt can ameliorate AP. The relative expression...
Autores principales: | Wang, Jianfa, Xu, Yayun, Jing, Hui, Chang, Qimeng, Wu, Xubo, Zhang, Ziping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291878/ https://www.ncbi.nlm.nih.gov/pubmed/34384137 http://dx.doi.org/10.1111/bcpt.13642 |
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