Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2‐Hydroxypropyl‐β‐Cyclodextrin Treatment

BACKGROUND: The etiology of Parkinson's disease (PD) is only partially understood despite the fact that environmental causes, risk factors, and specific gene mutations are contributors to the disease. Biallelic mutations in the phosphatase and tensin homolog (PTEN)‐induced putative kinase 1 (PI...

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Detalles Bibliográficos
Autores principales: Jarazo, Javier, Barmpa, Kyriaki, Modamio, Jennifer, Saraiva, Cláudia, Sabaté‐Soler, Sònia, Rosety, Isabel, Griesbeck, Anne, Skwirblies, Florian, Zaffaroni, Gaia, Smits, Lisa M., Su, Jihui, Arias‐Fuenzalida, Jonathan, Walter, Jonas, Gomez‐Giro, Gemma, Monzel, Anna S., Qing, Xiaobing, Vitali, Armelle, Cruciani, Gerald, Boussaad, Ibrahim, Brunelli, Francesco, Jäger, Christian, Rakovic, Aleksandar, Li, Wen, Yuan, Lin, Berger, Emanuel, Arena, Giuseppe, Bolognin, Silvia, Schmidt, Ronny, Schröder, Christoph, Antony, Paul M.A., Klein, Christine, Krüger, Rejko, Seibler, Philip, Schwamborn, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Regular Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9291890/
https://www.ncbi.nlm.nih.gov/pubmed/34637165
http://dx.doi.org/10.1002/mds.28810

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