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Assurance in vaccine efficacy clinical trial design based on immunological responses

The assurance of a future clinical trial is a key quantitative tool for decision‐making in drug development. It is derived from prior knowledge (Bayesian approach) about the clinical endpoint of interest, typically from previous clinical trials. In this paper, we examine assurance in the specific co...

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Detalles Bibliográficos
Autores principales: Callegaro, Andrea, Zahaf, Toufik, Tibaldi, Fabian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292007/
https://www.ncbi.nlm.nih.gov/pubmed/34254347
http://dx.doi.org/10.1002/bimj.202100015