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Ellagic acid and cilostazol ameliorate amikacin-induced nephrotoxicity in rats by downregulating oxidative stress, inflammation, and apoptosis

Amikacin (AK) has the largest spectrum of aminoglycosides. However, its use is constrained because of nephrotoxicity and ototoxicity. Ellagic acid (EA) is a polyphenol present in plants. It has antioxidant, anticarcinogenic, and antimutagenic characteristics. Cilostazol (CTZ) is a phosphodiesterase...

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Detalles Bibliográficos
Autores principales:	Saeed, Zeinab Mahmoud, Khattab, Monira Ismail, Khorshid, Nadia Esmat, Salem, Amal Elsayed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292089/ https://www.ncbi.nlm.nih.gov/pubmed/35849599 http://dx.doi.org/10.1371/journal.pone.0271591

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