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Generation of a ceramide synthase 6 mouse lacking the DDRSDIE C-terminal motif

The important membrane lipid, ceramide, is generated by a family of homologous enzymes, the ceramide synthases (CerSs), multi-spanning membrane proteins located in the endoplasmic reticulum. Six CerS isoforms exist in mammals with each using a subset of acyl-CoAs for (dihydro)ceramide synthesis. A n...

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Detalles Bibliográficos
Autores principales:	Kim, Jiyoon, Pewzner-Jung, Yael, Joseph, Tammar, Ben-Dor, Shifra, Futerman, Anthony H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292091/ https://www.ncbi.nlm.nih.gov/pubmed/35849604 http://dx.doi.org/10.1371/journal.pone.0271675

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