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Deletion of SM22α disrupts the structure and function of caveolae and T-tubules in cardiomyocytes, contributing to heart failure

AIMS: Smooth muscle 22-alpha (SM22α) is an actin-binding protein that plays critical roles in mediating polymerization of actin filaments and stretch sensitivity of cytoskeleton in vascular smooth muscle cells (VSMCs). Multiple lines of evidence indicate the existence of SM22α in cardiomyocytes. Her...

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Detalles Bibliográficos
Autores principales: Wu, Jun, Wang, Wei, Huang, Yaomeng, Wu, Haochen, Wang, Jiabin, Han, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292107/
https://www.ncbi.nlm.nih.gov/pubmed/35849583
http://dx.doi.org/10.1371/journal.pone.0271578

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