Cargando…
In silico investigation of Alsin RLD conformational dynamics and phosphoinositides binding mechanism
Alsin is a protein known for its major role in neuronal homeostasis and whose mutation is associated with early-onset neurodegenerative diseases. It has been shown that its relocalization from the cytoplasm to the cell membrane is crucial to induce early endosomes maturation. In particular, evidence...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292110/ https://www.ncbi.nlm.nih.gov/pubmed/35849605 http://dx.doi.org/10.1371/journal.pone.0270955 |