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Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection

Blocking Plasmodium, the causative agent of malaria, at the asymptomatic pre-erythrocytic stage would abrogate disease pathology and prevent transmission. However, the lack of well-defined features within vaccine-elicited antibody responses that correlate with protection represents a major roadblock...

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Detalles Bibliográficos
Autores principales: Visweswaran, Ganesh Ram R., Vijayan, Kamalakannan, Chandrasekaran, Ramyavardhanee, Trakhimets, Olesya, Brown, Samantha L., Vigdorovich, Vladimir, Yang, Ashton, Raappana, Andrew, Watson, Alex, Selman, William, Zuck, Meghan, Dambrauskas, Nicholas, Kaushansky, Alexis, Sather, D. Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292112/
https://www.ncbi.nlm.nih.gov/pubmed/35793394
http://dx.doi.org/10.1371/journal.ppat.1010671