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Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection
Blocking Plasmodium, the causative agent of malaria, at the asymptomatic pre-erythrocytic stage would abrogate disease pathology and prevent transmission. However, the lack of well-defined features within vaccine-elicited antibody responses that correlate with protection represents a major roadblock...
Autores principales: | Visweswaran, Ganesh Ram R., Vijayan, Kamalakannan, Chandrasekaran, Ramyavardhanee, Trakhimets, Olesya, Brown, Samantha L., Vigdorovich, Vladimir, Yang, Ashton, Raappana, Andrew, Watson, Alex, Selman, William, Zuck, Meghan, Dambrauskas, Nicholas, Kaushansky, Alexis, Sather, D. Noah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292112/ https://www.ncbi.nlm.nih.gov/pubmed/35793394 http://dx.doi.org/10.1371/journal.ppat.1010671 |
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