Zika virus-like particle vaccine fusion loop mutation increases production yield but fails to protect AG129 mice against Zika virus challenge

Zika virus (ZIKV) is a mosquito-borne flavivirus with maternal infection associated with preterm birth, congenital malformations, and fetal death, and adult infection associated with Guillain-Barré syndrome. Recent widespread endemic transmission of ZIKV and the potential for future outbreaks necess...

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Detalles Bibliográficos
Autores principales: Thompson, Danielle, Guenther, Ben, Manayani, Darly, Mendy, Jason, Smith, Jonathan, Espinosa, Diego A., Harris, Eva, Alexander, Jeff, Vang, Lo, Morello, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9292115/
https://www.ncbi.nlm.nih.gov/pubmed/35793354
http://dx.doi.org/10.1371/journal.pntd.0010588

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